Crohn's disease: Genetic susceptibility, bacteria, and innate immunity

Lancet

Volumn 357, Issue 9272, 2001, Pages 1902-1904

  Van Heel, David A ^a   McGovern, Dermot P B ^a   Jewell, Derek P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CORTICOSTEROID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

ANTIBIOTIC THERAPY; BACTERIAL IMMUNITY; BACTERIUM; CHROMOSOME 16; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; ENTERITIS; ENTEROBACTERIACEAE; EXPRESSED SEQUENCE TAG; FRAMESHIFT MUTATION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC SUSCEPTIBILITY; HUMAN; IMMUNE RESPONSE; KIDNEY CELL; MONOCYTE; NOTE; PATHOGENESIS; PRIORITY JOURNAL; RISK;

EID: 0035897905     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(00)05091-1     Document Type: Note

References (11)

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3. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
4. A frameshift mutation in Nod2 associated with susceptibility to Crohn's disease
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6. Human Nod1 confers responsiveness to bacterial lipopolysaccharides
7. Tumor necrosis factor: Biology and therapeutic inhibitors
8. Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
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10. Monocyte/macrophage activation by normal bacteria and bacterial products: Implications for altered epithelial function in Crohn's disease
11. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene