Antisense technology: Inaccessibility and non-specificity

Drug Discovery Today

Volumn 6, Issue 24, 2001, Pages 1260-1261

  Sohail, Muhammad ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; MESSENGER RNA; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBONUCLEASE H;

BINDING SITE; NOTE; SIDE EFFECT; TECHNIQUE; TECHNOLOGY;

EID: 0035892597     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1359-6446(01)02115-8     Document Type: Note

References (5)

1. Emerging antisense technologies for gene functionalization and drug discovery
2. Mapping of RNA accessible sites for antisense experiments with oligonucleotide libraries
3. Antisense oligonucleotides selected by hybridization to scanning arrays are effective reagents in vivo
4. Selecting optimal antisense reagents
5. Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides