Thymidine phosphorylase activity in nonsmall cell lung carcinoma tissues

Cancer

Volumn 92, Issue 10, 2001, Pages 2658-2661

  Toomey, Deirdre ^a   Smyth, Gordon ^a   Condron, Claire ^a   Kay, Elaine ^a   Conroy, Ronan ^a   Foley, Deirdre ^a   Hong, Chen ^a   Hogan, Brian ^a   Toner, Siobhan ^a   McCormick, Paul ^a   Broe, Patrick ^a   Kelly, Cathal ^a   Bouchier Hayes, David ^a  

^a BEAUMONT HOSPITAL   (Ireland)

Author keywords

Enzyme immunoassay; Nonsmall cell lung carcinoma; Thymidine phosphorylase; Tumor stroma

Indexed keywords

PROTEIN; THYMIDINE PHOSPHORYLASE;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER TISSUE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FEMALE; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MALE; PRIORITY JOURNAL; TUMOR DIFFERENTIATION;

ADULT; AGED; CARCINOMA, NON-SMALL-CELL LUNG; CELL DIFFERENTIATION; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; SMOKING; THYMIDINE PHOSPHORYLASE; TUMOR MARKERS, BIOLOGICAL;

EID: 0035889943     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20011115)92:10<2658::AID-CNCR1619>3.0.CO;2-3     Document Type: Article

References (11)

1. Identification of angiogenic activity and the cloning and expression of platelet-derived endothelial cell growth factor
2. Platelet-derived endothelial cell growth factor has thymidine phosphorylase activity
3. Vascular endothelial growth factor and Platelet derived endothelial cell growth factor are frequently coexpressed in highly vascularized human breast cancer
4. Activation of 5′-deoxy-5-fluorouridine by thymidine phosphorylase in human tumors
5. The degradation of 5′-deoxy-5-fluorouridine by pyrimidine nucleoside phosphorylase in normal and cancer tissue
6. Platelet-derived endothelial cell growth factor (thymidine phosphorylase) expression in lung cancer
7. Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small cell lung cancer
8. Different patterns of stromal and cancer cell thymidine phosphorylase reactivity in nonsmall-cell lung cancer: Impact on tumour neoangiogenesis and survival
9. Revisions in the International System for Staging Lung Cancer
10. Preparation of anti-human thymidine phosphorylase monoclonal antibodies useful for detecting the enzyme levels in tumor tissues
11. Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5 fluorouridine