Inactivation of rat liver cytochrome P450 (P450) by N,N-dimethylformamide and N,N-dimethylacetamide

Toxicology Letters

Volumn 124, Issue 1-3, 2001, Pages 101-111

  Tolando, Roberto ^a   Zanovello, Alberta ^a   Ferrara, Roberta ^a   Iley, Jim N ^b   Manno, Maurizio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b OPEN UNIVERSITY   (United Kingdom)

Author keywords

Cytochrome P450; Free radicals; Haem; N,N dimethylacetamide; N,N dimethylformamide; Protoporphyrin IX

Indexed keywords

ASCORBIC ACID; CARBON; CARBON MONOXIDE; CYTOCHROME P450; CYTOCHROME P450 2E1; FREE RADICAL; GLUTATHIONE; HEME; N TERT BUTYL ALPHA PHENYLNITRONE; N,N DIMETHYLACETAMIDE; N,N DIMETHYLFORMAMIDE; PROTOPORPHYRIN; PYRIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME INACTIVATION; GAS FLOW; LIVER MICROSOME; LIVER TOXICITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SPIN TRAPPING;

ACETAMIDES; ANIMALS; CRYOPROTECTIVE AGENTS; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DIMETHYLFORMAMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICALS; ISOENZYMES; MALE; MICROSOMES, LIVER; RATS; RATS, WISTAR;

EID: 0035887406     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(01)00384-8     Document Type: Article

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