Bidirectional electrogenic transport of peptides by the proton-coupled carrier PEPT1 in Xenopus laevis oocytes: Its asymmetry and symmetry

Journal of Physiology

Volumn 536, Issue 2, 2001, Pages 495-503

  Kottra, Gabor ^a,b   Daniel, Hannelore ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Institute of Nutritional Sciences   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; DIPEPTIDE DERIVATIVE; GLYCINE DERIVATIVE; MEMBRANE PROTEIN; PEPTIDE DERIVATIVE; PEPTIDE TRANSPORTER 1; PROTON; UNCLASSIFIED DRUG; DIPEPTIDE; GLYCYLGLYCINE;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CELL MEMBRANE POTENTIAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; COUPLING FACTOR; CYTOPLASM; ELECTRIC POTENTIAL; ELECTRICITY; ELECTRODE; FEMALE; MEASUREMENT; MEMBRANE CURRENT; MEMBRANE POTENTIAL; MICHAELIS MENTEN KINETICS; NONHUMAN; OOCYTE; PATCH CLAMP; PH; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN TRANSPORT; PROTON TRANSPORT; VOLTAGE CLAMP; XENOPUS LAEVIS; ANIMAL TISSUE; CYTOSOL; PROTON MOTIVE FORCE;

ANIMALS; BIOLOGICAL TRANSPORT; CARRIER PROTEINS; DIPEPTIDES; FEMALE; GENE EXPRESSION; HYDROGEN-ION CONCENTRATION; KINETICS; MEMBRANE POTENTIALS; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTONS; SYMPORTERS; XENOPUS LAEVIS;

EID: 0035887256     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.2001.0495c.xd     Document Type: Article

References (20)

1. +/peptide symporter PepT1 expressed in Xenopus laevis oocytes
2. Expression cloning and functional characterization of the kidney cortex high-affinity proton-coupled peptide transporter
3. Expression cloning of a cDNA from rabbit small intestine related to proton-coupled transport of peptides, beta-lactam antibiotics and ACE-inhibitors
4. Internal pH of Xenopus oocytes: A study of the mechanism and role of pH changes during meiotic maturation
5. Functional analysis of a chimeric mammalian peptide transporter derived from the intestinal and renal isoforms
6. Delta-aminolevulinic acid transport by intestinal and renal peptide transporters and its physiological and clinical implications
7. Minimal molecular determinants of substrates for recognition by the intestinal peptide transporter
8. Identification of a potential substrate binding domain in the mammalian peptide transporters PEPT1 and PEPT2 using PEPT1-PEPT2 and PEPT2-PEPT1 chimeras
9. Preferential recognition of zwitterionic dipeptides as transportable substrates by the high-affinity peptide transporter PEPT2
10. -) cotransport function. Steady state studies in giant Xenopus oocyte membrane patches
11. +/oligopeptide cotransporter hPEPT1 transports differently-charged dipeptides with identical electrogenic properties
12. +-coupled oligopeptide transporter hPEPT1
13. +-coupled oligopeptide cotransporter PepT1
14. Regulation mechanisms of intracellular pH of Xenopus laevis oocyte
15. +/glucose cotransporter (SGLT1)
16. Effects of glibenclamide on glycylsarcosine transport by the rat peptide transporters PEPT1 and PEPT2
17. Stoichiometry and pH dependence of the rabbit proton-dependent oligopeptide transporter PepT1
18. +/peptide cotransporters in rat renal brush-border membranes
19. Transport characteristics of differently charged cephalosporin antibiotics in oocytes expressing the cloned intestinal peptide transporter PepT1 and in human intestinal Caco-2 cells