Synovial fluid markers of osteoarthritis in dogs

Journal of the American Veterinary Medical Association

Volumn 219, Issue 6, 2001, Pages 756-761

  Fox, Derek B ^a   Cook, James L ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS;

BIOLOGICAL MARKER; CHONDROITIN SULFATE; KERATAN SULFATE; STROMELYSIN;

ANIMAL; ANIMAL DISEASE; ARTICLE; ARTICULAR CARTILAGE; CHEMISTRY; DISEASE MODEL; DOG; DOG DISEASE; FEMUR; METABOLISM; OSTEOARTHRITIS; PATHOLOGY; SYNOVIAL FLUID;

ANIMALS; BIOLOGICAL MARKERS; CARTILAGE, ARTICULAR; CHONDROITIN SULFATES; DISEASE MODELS, ANIMAL; DOG DISEASES; DOGS; FEMUR; KERATAN SULFATE; MATRIX METALLOPROTEINASE 3; OSTEOARTHRITIS; SYNOVIAL FLUID;

EID: 0035885811     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2001.219.756     Document Type: Article

References (43)

1. Johnston SA. Osteoarthritis: joint anatomy, physiology and pathobiology. Vet Clin North Am Small Anim Pract 1997;27:699-723.
2. Lipowitz AJ. Degenerative joint disease. In: Slatter D, ed. Textbook of small animal surgery. Philadelphia: WB Saunders Co, 1993;1921-1927.
3. Myers SL. Synovial fluid markers in osteoarthritis. Rheum Dis Clin North Am 1999;25:433-449.
4. Lohmander LS. Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease. J Anat 1994;184:477-487.
5. Lohmander LS. Markers of cartilage metabolism in arthrosis: a review. Acta Orthop Scand 1991;62:623-632.
6. Garnero P, Rousseau JC, Delmas PD. Molecular basis and clinical use of biochemical markers of bone, cartilage, and synovium in joint diseases. Arthritis Rheum 2000;43:953-968.
7. Brandt KD, Fife RS, Braunstein EM, et al. Radiographic grading of the severity of knee osteoarthritis: relation of the Kellegren and Lawrence grade to a grade based on joint space narrowing, and correlation with arthroscopic evidence of articular cartilage degeneration. Arthritis Rheum 1991;34:1381-1386.
8. Rørvik AM, Grøndahl M. Markers of osteoarthritis: a review of the literature. Vet Surg 1995;24:255-262.
9. Caterson B. Immunological aspects of markers of joint disease. J Rheumatol 1991;27(suppl):19-23.
10. Poole AC. The structure and function of articular cartilage matrices. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;1-36.
11. Mayne R, Brewton RG. Extracellular matrix of cartilage: collagen. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;81-108.
12. Neame PJ. Extracellular matrix of cartilage: proteoglycans. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;109-138.
13. Caterson B, Flannery CR, Hughes CE, et al. Mechanisms involved in cartilage proteoglycan catabolism. Matrix Biol 2000;19:333-344.
14. Fraser JR, Laurent TC, Laurent UB. Hyaluronan: its nature, distribution, functions and turnover. J Intern Med 1997;242:27-33.
15. Tzaicos C, Fraser JR, Tsotsis E, et al. Inhibition of hyaluronan uptake in lymphatic tissue by chondroitin sulphate proteoglycan. Biochem J 1989;264:823-828.
16. Laurent UB, Fraser JR, Engstrom-Laurent A, et al. Catabolism of hyaluronan in the knee joint of the rabbit. Matrix 1992;12:130-136.
17. Seibel MJ, Duncan A, Robins SO. Urinary hydroxy-pyridinium crosslinks provide indices of cartilage and bone involvement in arthritis diseases. J Rheumatol 1989;16:964-970.
18. Campion GV, McCrae F, Schnitzer TJ, et al. Levels of keratan sulfate in the serum and synovial fluid of patients with osteoarthritis of the knee. Arthritis Rheum 1991;34:1254-1259.
19. Myers SL, O'Connor BL, Brandt KD. Accelerated clearance of albumin from the osteoarthritic knee: implications for interpretation of concentrations of "cartilage markers" in synovial fluid. J Rheumatol 1996;23:1744-1748.
20. Ratcliffe A, Shurety W, Caterson B. The quantification of a native chondroitin sulfate epitope in synovial fluid lavages and articular cartilage from canine experimental osteoarthritis and disuse atrophy. Arthritis Rheum 1993;36:543-549.
21. Petersson IF, Sandqvist L, Svensson B et al. Cartilage markers in symptomatic knee osteoarthritis. Ann Rhuem Dis 1997;56:64-67.
22. Burton-Wurster N, Todhunter RJ, Lust G. Animal models of osteoarthritis. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;347-408.
23. Pond MJ, Nuki G. Experimentally-induced osteoarthritis in the dog. Ann Rheum Dis 1973;32:387-388.
24. Brandt KD, Myers SL, Burr D, et al. Osteoarthritic changes in canine articular cartilage, subchondral bone and synovium fifty-four months after transection of the anterior cruciate ligament. Arthritis Rheum 1991;34:1560-1570.
25. Panula HE, Lohmander LS, Ronkko S. Elevated levels of synovial fluid PLA2, stromelysin (MMP-3) and TIMP in early osteoarthrosis after tibial valgus osteotomy in young Beagle dogs. Acta Orthop Scand 1998;29:152-158.
26. Lindhorst E, Vail TP, Guilak F. Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis. J Orthop Res 2000;18:269-280.
27. Palmoski M, Perricone E, Brandt KD. Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization. Arthritis Rheum 1979;22:508-517.
28. Ratcliffe A, Billingham MEJ, Saed-Nejad F. Increased release of matrix components from articular cartilage in experimental canine osteoarthritis. J Orthop Res 1992;10:350-358.
29. Ratcliffe A, Beauvais PJ, Saed-Nejad F. Synovial fluid analyses detect and differentiate proteoglycan metabolism in canine experimental models of osteoarthritis and disuse atrophy. Agents Actions Suppl 1993;39:63-67.
30. Arican M, Carter SD, Bennet D. Measurement of glycosaminoglycans and keratan sulphate in canine arthropathies. Res Vet Sci 1994;56:290-297.
31. Innes JF, Sharif M, Barr ARS. Relations between biochemical markers of osteoarthritis and other disease parameters in a population of dogs with naturally acquired osteoarthritis of the genual joint. Am J Vet Res 1998;59:1530-1536.
32. Innes JF, Sharif M, Barr ARS. Changes in concentrations of biochemical markers of osteoarthritis following surgical repair of ruptured cranial cruciate ligaments in dogs. Am J Vet Res 1999;60:1164-1168.
33. Belcher C, Yaqub R, Fawthrop F, et al. Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans and hyaluronan in arthritic and normal knees. Ann Rheum Dis 1997;56:299-307.
34. Visco DM, Johnstone B, Hill MA, et al. Immunohistochemical analysis of 3-B-3(-) and 7-D-4 epitope expression in canine osteoarthritis. Arthritis Rheum 1993;12:1718-1725.
35. Myers SL, Brandt KD, O'Connor BL, et al. Synovitis and osteoarthritic changes in canine articular cartilage after anterior cruciate ligament transection: effects of surgical hemostasis. Arthritis Rheum 1990;33:1406-1415.
36. Nagase K, Woessner JF. Role of endogenous proteinases in the degradation of cartilage matrix. In: Woessner JF, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker Inc, 1993;159-186.
37. Spreng D, Sigrist N, Busato A, et al. Stromelysin activity in canine cranial cruciate ligament rupture. Vet Comp Orthop Traumatol 1999;12:159-165.
38. Lark MW, MacNaul KA, Donatelli S, et al. Induction of increased levels of proteoglycan fragments in synovial fluid (SF) and increased levels of stromelysin in cartilage, synovium and SF by intraarticular injection of canine monocyte conditioned medium into dogs. J Rheumatol 1994;21:1716-1724.
39. Pickvance E, Oegema TR, Thompson RC. Immunolocalization of selected cytokines and proteases in canine articular cartilage after transarticular loading. J Orthop Res 1993;11:313-323.
40. Kammermann JR, Kincaid SA, Rumph PF. Tumor necrosis factor-alpha (TNF-alpha) in canine osteoarthritis: immunolocalization of TNF-alpha, stromelysin and TNF receptors in canine osteoarthritic cartilage. Osteoarthritis Cartilage 1996;4:23-34.
41. Cook JL, Anderson CC, Kreeger JM, et al. Effects of human recombinant interleukin-1β on canine articular chondrocytes in three-dimensional culture. Am J Vet Res 2000;61:766-770.
42. Brama PA, Tekoppele JM, Beekman B, et al. Influence of development and joint pathology on stromelysin enzyme activity in equine synovial fluid. Ann Rheum Dis 2000;59:155-157.
43. Lohmander LS, Hoerrner LA, Lark MW. Metalloproteinases, tissue inhibitor, and proteoglycan fragments in knee synovial fluid in human osteoarthritis. Arthritis Rheum 1993;36:181-189.