Peripheral regulation of graft-versus-host alloreactivity in mixed chimeric miniature swine

Transplantation

Volumn 72, Issue 3, 2001, Pages 523-526

  Kunisaki, Shaun M ^a   Haller, Gary W ^a   Fuchimoto, Yasushi ^a,b   Huang, Christene A ^a   Sachs, David H ^a   Tenderich, G ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b TOKYO METROPOLITAN CHILDREN'S MEDICAL CENTER   (Japan)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOIMMUNITY; ANIMAL EXPERIMENT; ARTICLE; CHIMERA; COCULTURE; CONTROLLED STUDY; GRAFT VERSUS HOST REACTION; MAJOR HISTOCOMPATIBILITY COMPLEX; MIXED LYMPHOCYTE REACTION; NONHUMAN; PERIPHERAL BLOOD STEM CELL; PRIORITY JOURNAL; RADIOSENSITIVITY; SWINE; T LYMPHOCYTE;

EID: 0035881970     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200108150-00027     Document Type: Article

References (11)

1. Mixed chimerism and tolerance without whole body irradiation in a large animal model
2. Stable mixed chimerism and tolerance using a non-myeloablative preparative regimen in a large animal model
3. Mechanism of protection from graft-versus-host disease in murine mixed allogeneic chimeras: I. Development of a null cell population suppressive of CML responses and derived from the syngeneic bone marrow compartment
4. Mixed lymphohematopoietic chimerism and graft-vs-lymphoma effects are achievable in adult recipients following non-myeloablative therapy and HLA-mismatched donor bone marrow transplantation
5. Protection from graft-versus-host disease in fully allogeneic chimeras by prior administration of T cell-depleted syngeneic bone marrow
6. Induction of specific tolerance to class I disparate renal allografts in miniature swine with cyclosporine
7. In vivo T cell depletion in miniature swine using swine CD3 immunotoxin, pCD3-CRM9
8. An allelic non-histocompatibility antigen with wide tissue distribution as a marker for chimerism in pigs
9. Peripheral tolerance to class I mismatched renal allografts in miniature swine: Donor antigen-activated peripheral blood lymphocytes from tolerant swine inhibit antidonor CTL reactivity
10. Clones natural suppressor cells prevent lethal graft-versus-host disease
11. Identification of donor-derived antigen-specific suppressor cells in murine bone marrow chimeras prepared with total-lymphoid irradiation