Physiologically based modeling of nonsteady state dermal absorption of halogenated methanes from an aqueous solution

Toxicology and Applied Pharmacology

Volumn 144, Issue 2, 1997, Pages 315-324

  Jepson, Gary W ^a   McDougal, James N ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROFORM; DIBROMOMETHANE; HALOGENATED HYDROCARBON;

ANIMAL EXPERIMENT; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; MALE; MODEL; NONHUMAN; RAT; SKIN ABSORPTION; SKIN PERMEABILITY;

EID: 0031172665     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1006/taap.1997.8143     Document Type: Article

References (27)

1. 2 - in the rat. Toxicologist 4, 111.
2. Andersen, M. E., and Keller, W. C. (1984). Toxicokinetic principles in relation to percutaneous absorption and cutaneous toxicity. In Cutaneous Toxicity (V. A. Drill and P. Lazar, Eds.), pp. 9-27. Raven Press, New York.
3. Bogen, K. T., Colston, B. W., Jr., and Machicao, L. K. (1994). Percutaneous absorption of dilute aqueous chlorinated organic solvents in the hairless guinea pig. In Water Contamination and Health (R. G. M. Wang, Ed.), pp. 323-345. Dekker, New York.
4. Chinery, R. L., and Gleason, A. K. (1993). A compartmental model for the prediction of breath concentration and absorbed dose of chloroform after exposure while showering. Risk Anal. 13(1), 51-62.
5. Cleek, R. L., and Bunge, A. L. (1993). A New method for estimating dermal absorption from chemical exposure. 1. General approach. Pharm. Res. 10(4), 497-506.
6. Crank, J. (1975). The Mathematics of Diffusion, 2nd edition, pp. 44-56, Clarendon, Oxford, UK.
7. Fraga, C. G., Liebovitz, B. E., and Tappel, A. L. (1987). Halogenated compounds as inducers of lipid peroxidation in tissue slices. Free Radical Biol. Med. 3(2), 119-23.
8. Gargas, M. L., and Andersen, M. E. (1989). Determining kinetic constants of chlorinated ethane metabolism in the rat from rates of exhalation. Toxicol. Appl. Pharmacol. 99(2), 344-53.
9. Gargas, M. L., Clewell, H. J., and Andersen, M. E. (1986). Metabolism of inhaled dihalomethanes in vivo: Differentiation of kinetic constants for two independent pathways. Toxicol. Appl. Pharmacol. 82, 211-223.
10. Gargas, M. L., Burgess, R. J., Voisard, D. E., Cason, G. H., and Andersen, M. E. (1989). Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues. Toxicol. Appl. Pharmacol. 98, 87-99.
11. Islam, M. S., Zhao, L., McDougal, J. N., and Flynn, G. L. (1995). Uptake of chloroform by skin during short exposures to contaminated water. Risk Anal. 15(3), 343-351.
12. Kedderis, L. B., Mills, J. J., Andersen, M. E., and Birnbaum, L. S. (1993). A physiologically based pharmacokinetic model for 2,3,7,8-tetrabromodibenzo-p-dioxin (TBDD) in the rat: Tissue distribution and CYP1A induction. Toxicol. Appl. Pharmacol. 121, 87-98.
13. Kubic, V. L., and Anders, M. W. (1975). Metabolism of dihalomethanes to carbon monoxide. III. In vitro studies. Drug. Metab. Dispos. 3(2), 104-112.
14. Leung, H. W., and Paustenbach, D. J. (1994). Techniques for estimating the percutaneous absorption of chemicals due to occupational and environmental exposure. Appl. Occup. Environ. Hyg. 9(3), 187-197.
15. McDougal, J. N., George, M. E., Clewell, H. J., III, Andersen, M. E., and Pollard, D. L. (1985). Dermal Absorption of Hydrazine Vapors, pp. 299-305. CPIA Publication 436.
16. McDougal, J. N., Jepson, G. W., Clewell, H. J., MacNaughton, M. G., and Andersen, M. E. (1986). A physiological pharmacokinetic model for dermal absorption of vapors in the rat. Toxicol. Appl. Pharmacol. 85, 286-294.
17. McDougal, J. N., and Clewell, H. J. (1990). Dermal to inhalation extrapolation for organic chemicals. In Principles of Route-to-Route Extrapolation for Risk Assessment (T. R. Gerrity and C. J. Henry, Eds.), pp. 313-317, Elsevier.
18. McKone, T. E., and Howd, R. A. (1992). Estimating dermal uptake of nonionic organic chemicals from water and soil. I. Unified fugacity-based models for risk assessments. Risk Anal. 12(4), 543-557.
19. Morgan, D. L., Cooper, S. W., Carlock, D. L., Sykora, J. J., Sutton, B., Mattie, D. R., and McDougal, J. N. (1991). Dermal absorption of neat and aqueous volatile organic chemicals in the Fischer 344 rat. Environ. Res. 55, 51-63.
20. Ostermann-Golkar, S., Hussain, S., Walles, S., Anderstam, B., and Sigvardsson, K. (1983). Chemical reactivity and mutagenicity of some dihalomethanes. Chem. Biol. Interact. 46(1), 121-30.
21. Ramsey, J. C., and Andersen, M. E. (1984). A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans. Toxicol. Appl. Pharmacol. 73, 159-175.
22. Rao, H. V., and Brown, D. R. (1993). A physiologically based pharmacokinetic assessment of tetrachloroethylene in groundwater for a bathing and showering determination. Risk Anal. 13(1), 37-49.
23. Roldan-Arjona, T., and Pueyo, C. (1993). Mutagenic and lethal effects of halogenated methanes in the ara test of salmonella typhimurium: Quantitative relationship with chemical activity. Mutagenesis 8(2), 127-31.
24. Scheuplein, R. J. (1977). Permeability of the Skin. In Handbook of Physiology: Reactions to Environmental Agents (D. K. H. Lee, H. L. Falk, S. D. Murphy, and S. R. Geiger, Eds.), pp. 299-322. American Physiological Society, Bethesda MD.
25. Scheuplein, R. J., and Blank, I. H. (1971). Permeability of the skin. Physiol. Rev. 51, 702-747.
26. Scheuplein, R. J., and Bronaugh, R. L. (1983). In Biochemistry and Physiology of the Skin (L. A. Goldsmith, Ed.), Vol. 2, pp. 1255-1295. Oxford Univ. Press, Oxford, UK.
27. Shyr, L. J., Sabourin, P. J., Medinsky, M. A., Birnbaum, L. S., and Henderson, R. F. (1993). Physiologically based modeling of 2-butoxyethanol disposition in rats following different routes of exposure. Environ. Res. 63, 202-218.