Glycolipid-enriched membrane domains are assembled into membrane patches by associating with the actin cytoskeleton

Experimental Cell Research

Volumn 267, Issue 2, 2001, Pages 173-183

  Rodgers, William ^a,b   Zavzavadjian, Joelle ^b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

F actin; GEM domains; GFP; Lck; Lipid rafts; Membrane capping; T cells

Indexed keywords

CHOLESTEROL; DETERGENT; F ACTIN; GLYCOLIPID; GREEN FLUORESCENT PROTEIN; PROTEIN P56; TRITON X 100;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL LYSATE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSKELETON; HELA CELL; HUMAN; HUMAN CELL; LIPID MEMBRANE; MEMBRANE STRUCTURE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 0035879095     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2001.5253     Document Type: Article

References (34)

1. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface
2. Signals determining protein tyrosine kinase and glycosyl-phosphatidylinositol-anchored protein targeting to a glycolipid-enriched membrane fraction
3. fyn mediates interaction with glycosyl-phosphatidylinositol-anchored proteins
4. lck deficiency on the growth and cytolytic effector function of an interleukin-2-dependent cytotoxic T-cell line
5. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor
6. Lipid rafts and signal transduction
7. Distribution of a glycosylphosphatidylinositol-anchored protein at the apical surface of MDCK cells examined at a resolution of <100 Å using imaging fluorescence resonance energy transfer
8. GPI-anchored proteins are organized in submicron domains at the cell surface
9. 2+-signaling competent
10. The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain
11. Use of polymerase chain reaction epitope tagging for protein tagging in Saccharomyces cerevisiae
12. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase
13. lck associated with glycolipid-enriched membrane domains
14. Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism
15. Critical role for cholesterol in lyn-mediated tyrosine phosphorylation of FcεRI and their association with detergent-resistant membranes
16. Lateral motion of fluorescently labeled acetylcholine receptors in membranes of developing muscle fibers
17. Trafficking of endothelial nitric-oxide synthase in living cells. Quantitative evidence supporting the role of palmitoylation as a kinetic trapping mechanism limiting membrane diffusion
18. 3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae
19. Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase
20. Phosphorylation of serine 59 of p561ck in activated T cells
21. Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes
22. Lipid domain structure of the plasma membrane revealed by patching of membrane components
23. Cytochalasin D does not produce net depolymerization of actin filaments in HEp-2 cells
24. Action of cytochalasin D on cytoskeletal networks
25. Looking at lipid rafts?
26. Endocytosis of GPI-anchored proteins in human lymphocytes: Role of glycolipid-based domains, actin cytoskeleton, and protein kinases
27. Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton
28. Mobility measurement by analysis of fluorescence photobleaching recovery kinetics
29. T lymphocyte costimulation mediated by reorganization of membrane microdomains
30. Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor
31. Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: Accumulation of actin regulated by local tyrosine phosphorylation
32. Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains
33. A role for lipid rafts in B cell antigen receptor signaling and antigen targeting