Translocation (2;14) associated with complex rearrangements of the Ig heavy chain in non-Hodgkin lymphoma

Cancer Genetics and Cytogenetics

Volumn 128, Issue 2, 2001, Pages 137-140

  Walker, Logan C ^a   Morrison, Mary J ^a   Parfitt, Richard ^b   Crossen, Peter E ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b WELLINGTON HOSPITAL   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMBUCIL; IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; PREDNISONE; PROTEIN BCL 6;

AGED; ANALYTIC METHOD; ARTICLE; CASE REPORT; CELL DIVISION; CHROMOSOME 2; CLINICAL FEATURE; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENHANCER REGION; FEMALE; GENE ISOLATION; GENE LOCUS; GENE PROBE; GENE REARRANGEMENT; GENE SEQUENCE; GENE SWITCHING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; KARYOTYPE; KARYOTYPING; LYMPHOID CELL; MOLECULAR CLONING; NONHODGKIN LYMPHOMA; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

BLOTTING, SOUTHERN; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 2; CLONING, MOLECULAR; DNA-BINDING PROTEINS; FEMALE; GENE REARRANGEMENT; GENES, IMMUNOGLOBULIN; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOMA, NON-HODGKIN; MIDDLE AGED; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-6; TRANSCRIPTION FACTORS; TRANSLOCATION, GENETIC;

EID: 0035878550     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(01)00399-5     Document Type: Article

References (23)

1. Chromosomal translocations in human cancer
2. Two 14q+ chromosomes in malignant lymphoma: Crucial cytogenetic changes on 14q
3. Cytogenetic and histologic correlations in malignant lymphoma
4. Chromosome abnormalities in malignant lymphoma in patients from Saitama
5. Morphology in Ki-1 (CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35)
6. A rapid banding technique for human chromosomes
7. XbaI RFLP of ETS-1 oncogene in chronic B-cell leukaemia
8. Structure of the human immunoglobulin mu locus: Characterization of embryonic and rearranged J and D genes
9. Cloning the chromosomal breakpoint of t(14;18) human lymphomas: Clustering around JH on chromosome 14 and near a transcriptional unit on 18
10. Cloning and sequencing of a t(14;19) breakpoint that involves the Cu switch region
11. BCL3, the gene involved in the 14;19 translocation in chronic lymphocytic leukemia, is related to genes involved in cell cycle control and cell-lineage determination
12. Identification of heterologous translocation partner genes fused to the BCL6 gene in diffuse large B-cell lymphomas: 5′-RACE and LAPCR analyses of biopsy samples
13. Identification and characterization of BCL6 translocation partner genes in primary gastric high-grade B-cell lymphoma: Heat shock protein 89 alpha is a novel fusion partner gene of BCL6
14. Identification of the gene associated with the recurring chromosomal translocations t(3;14)(q27;q32) and t(3;22)(q27;q11) in B-cell lymphomas
15. Deregulation of BCL6 in non-Hodgkin lymphoma by insertions of IGH sequences in complex translocations involving band 3q27
16. Cloning of a breakpoint cluster region at band 3q27 involved in human non-Hodgkins lymphoma
17. LAZ3, a novel zinc-finger encoding gene, is disrupted by recurring chromosome 3q27 translocations in human lymphomas
18. Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma
19. Molecular mechanism of the t(14;18) - A model for lymphoid-specific chromosomal translocations
20. Aberrant rearrangements of the immunoglobulin heavy chain switch region in chronic B-cell leukemia
21. Detection of aberrant isotype switch recombination in low-grade and high-grade gastric MALT lymphomas
22. Promiscuous translocations into immunoglobulin heavy chain switch regions in multiple myeloma