Overexpression of parathyroid hormone-related protein promotes cell growth in the rat intestinal cell line IEC-6

Regulatory Peptides

Volumn 99, Issue 2-3, 2001, Pages 169-174

  Ye, Y ^a   Falzon, M ^a   Seitz, P K ^a   Cooper, C W ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

GI epithelium; Nuclear localization signal; Transfection

Indexed keywords

COMPLEMENTARY DNA; PARATHYROID HORMONE RELATED PROTEIN; THYMIDINE; TRITIUM;

ANIMAL CELL; ARTICLE; CELL CLONE; CELL GROWTH; CELL METABOLISM; CELL PROLIFERATION; CONTROLLED STUDY; CRYPT CELL; DNA SYNTHESIS; GENETIC TRANSFECTION; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; PROTEIN SYNTHESIS; RAT; REGULATORY MECHANISM;

ANIMALS; CELL DIVISION; CELL LINE; GENETIC VECTORS; HUMANS; NUCLEAR LOCALIZATION SIGNALS; PARATHYROID HORMONE-RELATED PROTEIN; PEPTIDE FRAGMENTS; PROTEIN BIOSYNTHESIS; PROTEINS; RATS; SEQUENCE DELETION; TRANSFECTION;

EID: 0035876844     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-0115(01)00248-8     Document Type: Article

References (21)

1. Parathyroid hormone-related protein purified from a human lung cancer cell line
2. Humoral hypercalcemia of cancer: Identification of a novel parathyroid hormone-like peptide
3. The physiology of parathyroid hormone-related protein: An emerging role as a developmental factor
4. Parathyroid hormone-related protein is a possible autocrine growth inhibitor for lymphocytes
5. Parathyroid hormone-related protein, an autocrine growth inhibitor of alveolar type II cells
6. Differential effects of continuous and transient treatment with parathyroid hormone-related peptide (PTHrP) on bone collagen synthesis
7. Parathyroid hormone-related protein is an autocrine modulator of rabbit proximal tubule cell growth
8. Co-purification of calcium transport-stimulating and DNA synthesis-stimulating agents with parathormone-like activity isolated from the hypercalcemic strain of the Walker 256 tumor
9. Endogenous parathyroid hormone-related peptide enhances proliferation and inhibits differentiation in the osteoblast-like cell line ROS 17/2.8
10. Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
11. Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
12. Widespread expression of the parathyroid hormone-related peptide and PTH/PTHrP receptor genes in intestinal epithelial cells
13. Nuclear Localization of the type 1 PTH/PTHrP receptor in rat tissues
14. Epitheloid cell cultures from rat small intestine
15. Parathyroid hormone-related peptide production and action in a myoepithelial cell line derived from normal human breast
16. Nucleolar localization of parathyroid hormone-related peptide enhances survival of chondrocytes under conditions that promotes apoptotic cell death
17. The nuclear targeting signal (NTS) of parathyroid hormone related protein mediates endocytosis and nucleolar translocation
18. Opposing mitogenic and anti-mitogenic actions of parathyroid hormone-related protein in vascular smooth muscle cells: A critical role for nuclear targeting
19. The nucleus: A target site for parathyroid hormone-related peptide (PTHrP) action
20. Parathyroid hormone-related protein in the pancreatic islet and the cardiovascular system
21. Parathyroid hormone-related protein overexpression in a rat intestinal cell line enhances apoptosis