Tight binding of the angiotensin AT1 receptor antagonist [3H]candesartan is independent of receptor internalization

Biochemical Pharmacology

Volumn 61, Issue 10, 2001, Pages 1227-1235

  Fierensa, Frederik L P ^a   Vanderheyden, Patrick M L ^a   Roggeman, Chantal ^a   De Backer, Jean Paul ^a   Thekkumkara, Thomas J ^b   Vauquelin, Georges ^a  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

Angiotensin AT1 receptor; Candesartan; CHO cells; Insurmountable antagonist; Internalization; Sucrose

Indexed keywords

ACID; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; CANDESARTAN; SUCROSE;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BINDING KINETICS; CELL SURFACE; CELLULAR DISTRIBUTION; CHO CELL; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BENZIMIDAZOLES; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CHO CELLS; CRICETINAE; ENDOCYTOSIS; GENE DELETION; INOSITOL PHOSPHATES; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; TETRAZOLES; THYMIDINE; TRITIUM;

EID: 0035873968     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(01)00614-1     Document Type: Article

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