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Volumn 1457, Issue 3, 2000, Pages 166-174

Mitochondrial protonophoric activity induced by a thyromimetic fatty acid analogue

Author keywords

Fatty acid; Mitochondria; Thyroid hormone; Uncoupling

Indexed keywords

3,3,14,14 TETRAMETHYLHEXADECANEDIOIC ACID; CALCIUM; CYCLOSPORIN A; FATTY ACID DERIVATIVE; THYROID HORMONE;

EID: 0034640041     PISSN: 00052728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2728(00)00097-9     Document Type: Article
Times cited : (13)

References (48)
  • 1
    • 0027384310 scopus 로고
    • Effect of fatty acids on energy coupling processes in mitochondria
    • Wojtczak L., Schönfeld P. Effect of fatty acids on energy coupling processes in mitochondria. Biochim. Biophys. Acta. 1183:1993;41-57.
    • (1993) Biochim. Biophys. Acta , vol.1183 , pp. 41-57
    • Wojtczak, L.1    Schönfeld, P.2
  • 2
    • 0030854715 scopus 로고    scopus 로고
    • Cellular energy utilization and molecular origin of standard metabolic rate in mammals
    • Rolfe D.F.S., Brown G.C. Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol. Rev. 77:1997;731-758.
    • (1997) Physiol. Rev. , vol.77 , pp. 731-758
    • Rolfe, D.F.S.1    Brown, G.C.2
  • 3
    • 0028053663 scopus 로고
    • Recent progress on regulation of the mitochondrial permeability transition pore, a cyclosporin-sensitive pore in the inner mitochondrial membrane
    • Bernardi P., Broekemeier D.R., Pfeiffer J. Recent progress on regulation of the mitochondrial permeability transition pore, a cyclosporin-sensitive pore in the inner mitochondrial membrane. J. Bioenerg. Biomembr. 26:1994;509-517.
    • (1994) J. Bioenerg. Biomembr. , vol.26 , pp. 509-517
    • Bernardi, P.1    Broekemeier, D.R.2    Pfeiffer, J.3
  • 4
    • 0029116916 scopus 로고
    • The mitochondrial permeability transition
    • Zorrati M., Szabo I. The mitochondrial permeability transition. Biochim. Biophys. Acta. 1241:1995;139-176.
    • (1995) Biochim. Biophys. Acta , vol.1241 , pp. 139-176
    • Zorrati, M.1    Szabo, I.2
  • 5
    • 0032504709 scopus 로고    scopus 로고
    • Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
    • Halestrap A.P., Kerr P.M., Javadov S., Woodfield K.Y. Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart. Biochim. Biophys. Acta. 1366:1998;79-94.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 79-94
    • Halestrap, A.P.1    Kerr, P.M.2    Javadov, S.3    Woodfield, K.Y.4
  • 6
    • 0022256692 scopus 로고
    • Inhibition of lipid synthesis by β,β′-tetramethyl-substituted C14-C22 α,ω dicarboxylic acids in the rat in vivo
    • Bar-Tana J., Kahn-Rose G., Srebnik M. Inhibition of lipid synthesis by β,β′-tetramethyl-substituted C14-C22 α,ω dicarboxylic acids in the rat in vivo. J. Biol. Chem. 260:1985;8404-8410.
    • (1985) J. Biol. Chem. , vol.260 , pp. 8404-8410
    • Bar-Tana, J.1    Kahn-Rose, G.2    Srebnik, M.3
  • 7
    • 0032512651 scopus 로고    scopus 로고
    • Mitochondrial uncoupling by long chain fatty acyl analogue
    • Hermesh O., Kalderon B., Bar-Tana J. Mitochondrial uncoupling by long chain fatty acyl analogue. J. Biol. Chem. 273:1998;3937-3942.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3937-3942
    • Hermesh, O.1    Kalderon, B.2    Bar-Tana, J.3
  • 8
    • 0344110248 scopus 로고    scopus 로고
    • Protonophoric activity of fatty acid analogs and derivatives in inner mitochondrial membrane: A further argument for fatty acid cycling model
    • Wojtczak L., Wieckowski M.R., Schönfeld P. Protonophoric activity of fatty acid analogs and derivatives in inner mitochondrial membrane: a further argument for fatty acid cycling model. Arch. Biochem. Biophys. 357:1998;76-84.
    • (1998) Arch. Biochem. Biophys. , vol.357 , pp. 76-84
    • Wojtczak, L.1    Wieckowski, M.R.2    Schönfeld, P.3
  • 9
    • 0025930608 scopus 로고
    • Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation
    • Skulachev V.P. Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation. FEBS Lett. 294:1991;158-162.
    • (1991) FEBS Lett. , vol.294 , pp. 158-162
    • Skulachev, V.P.1
  • 10
    • 0027945163 scopus 로고
    • + transport by free fatty acids which is further stimulated by mersalyl
    • + transport by free fatty acids which is further stimulated by mersalyl. J. Biol. Chem. 269:1994;27329-27336.
    • (1994) J. Biol. Chem. , vol.269 , pp. 27329-27336
    • Brustovetsky, N.1    Klingenberg, M.2
  • 11
    • 0031590634 scopus 로고    scopus 로고
    • Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier
    • Schönfeld P., Bohnensack R. Fatty acid-promoted mitochondrial permeability transition by membrane depolarization and binding to the ADP/ATP carrier. FEBS Lett. 420:1997;167-170.
    • (1997) FEBS Lett. , vol.420 , pp. 167-170
    • Schönfeld, P.1    Bohnensack, R.2
  • 13
    • 0027260708 scopus 로고
    • Thyroid hormone action on mitochondrial energy transfer
    • Soboll S. Thyroid hormone action on mitochondrial energy transfer. Biochim. Biophys. Acta. 1144:1993;1-16.
    • (1993) Biochim. Biophys. Acta , vol.1144 , pp. 1-16
    • Soboll, S.1
  • 14
    • 0027227273 scopus 로고
    • The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status
    • Harper M.E., Brand M.D. The quantitative contributions of mitochondrial proton leak and ATP turnover reactions to the changed respiration rates of hepatocytes from rats of different thyroid status. J. Biol. Chem. 268:1993;14850-14860.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14850-14860
    • Harper, M.E.1    Brand, M.D.2
  • 15
    • 0032479465 scopus 로고    scopus 로고
    • Decrease in mitochondrial energy coupling by thyroid hormones: A physiological effect rather than a pathological hyperthyroidism consequence
    • Bobyleva V., Pazienza T.L., Maseroli R., Tomasi A., Salvioli S., Cossarizza S., Franceschi C., Skulachev V.P. Decrease in mitochondrial energy coupling by thyroid hormones: a physiological effect rather than a pathological hyperthyroidism consequence. FEBS Lett. 430:1998;409-413.
    • (1998) FEBS Lett. , vol.430 , pp. 409-413
    • Bobyleva, V.1    Pazienza, T.L.2    Maseroli, R.3    Tomasi, A.4    Salvioli, S.5    Cossarizza, S.6    Franceschi, C.7    Skulachev, V.P.8
  • 16
    • 0026778138 scopus 로고
    • Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver
    • Kalderon B., Hertz R., Bar-Tana J. Effect of thyroid hormone treatment on redox and phosphate potentials in rat liver. Endocrinology. 131:1992;400-407.
    • (1992) Endocrinology , vol.131 , pp. 400-407
    • Kalderon, B.1    Hertz, R.2    Bar-Tana, J.3
  • 17
    • 0025319665 scopus 로고
    • Role of calcium ion in regulation of mammalian intramitochondrial metabolism
    • McCormack J.G., Halestrap A.P., Denton R.M. Role of calcium ion in regulation of mammalian intramitochondrial metabolism. Physiol. Rev. 70:1990;391-425.
    • (1990) Physiol. Rev. , vol.70 , pp. 391-425
    • McCormack, J.G.1    Halestrap, A.P.2    Denton, R.M.3
  • 18
    • 0017089948 scopus 로고
    • Relationship between configuration, function, and permeability in calcium-treated mitochondria
    • Hunter D.R., Haworth R.A., Southard J.H. Relationship between configuration, function, and permeability in calcium-treated mitochondria. J. Biol. Chem. 251:1976;5069-5077.
    • (1976) J. Biol. Chem. , vol.251 , pp. 5069-5077
    • Hunter, D.R.1    Haworth, R.A.2    Southard, J.H.3
  • 19
    • 0029561991 scopus 로고
    • Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: Relationship between pore opening and the activity of mitochondrial phospholipases
    • Broekemeier K.M., Pfeiffer D.R. Inhibition of the mitochondrial permeability transition by cyclosporin A during long time frame experiments: relationship between pore opening and the activity of mitochondrial phospholipases. Biochemistry. 34:1995;16440-16449.
    • (1995) Biochemistry , vol.34 , pp. 16440-16449
    • Broekemeier, K.M.1    Pfeiffer, D.R.2
  • 20
    • 0032570563 scopus 로고    scopus 로고
    • Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore
    • Wieckowski M.R., Wojtczak L. Fatty acid-induced uncoupling of oxidative phosphorylation is partly due to opening of the mitochondrial permeability transition pore. FEBS Lett. 423:1998;339-342.
    • (1998) FEBS Lett. , vol.423 , pp. 339-342
    • Wieckowski, M.R.1    Wojtczak, L.2
  • 21
    • 0029129103 scopus 로고
    • Mitochondrial permeability transition is induced by in vivo thyroid hormone treatment
    • Kalderon B., Hermesh O., Bar-Tana J. Mitochondrial permeability transition is induced by in vivo thyroid hormone treatment. Endocrinology. 136:1995;3552-3556.
    • (1995) Endocrinology , vol.136 , pp. 3552-3556
    • Kalderon, B.1    Hermesh, O.2    Bar-Tana, J.3
  • 23
    • 0032504717 scopus 로고    scopus 로고
    • From calcium signaling to cell death: Two conformations for the mitochondrial permeability transition pore. Switching from low- To high-conductance state
    • Ichas F., Mazat J.-P. From calcium signaling to cell death: two conformations for the mitochondrial permeability transition pore. Switching from low- to high-conductance state. Biochim. Biophys. Acta. 1366:1998;33-50.
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 33-50
    • Ichas, F.1    Mazat, J.-P.2
  • 24
    • 0025193488 scopus 로고
    • 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix-peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase
    • 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix-peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase. Biochem. J. 268:1990;153-160.
    • (1990) Biochem. J. , vol.268 , pp. 153-160
    • Halestrap, A.P.1    Davidson, A.M.2
  • 25
    • 0018337795 scopus 로고
    • The measurement of membrane potentials and ΔpH in cells, organelles, and vesicles
    • Rotenberg H. The measurement of membrane potentials and ΔpH in cells, organelles, and vesicles. Methods Enzymol. 55:1979;547-569.
    • (1979) Methods Enzymol. , vol.55 , pp. 547-569
    • Rotenberg, H.1
  • 27
    • 0020136308 scopus 로고
    • A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions
    • Bers D.M.A. A simple method for the accurate determination of free [Ca] in Ca-EGTA solutions. Am. J. Physiol. 242:1982;C404-C408.
    • (1982) Am. J. Physiol. , vol.242 , pp. 404-C408
    • Bers, D.M.A.1
  • 28
    • 0028095807 scopus 로고
    • Mitochondrial calcium transport: Physiological and pathological relevance
    • Gunter T.E., Gunter K.K., Sheu S.-S., Gavin C.F. Mitochondrial calcium transport: physiological and pathological relevance. Am. J. Physiol. 267:1994;C313-C339.
    • (1994) Am. J. Physiol. , vol.267 , pp. 313-C339
    • Gunter, T.E.1    Gunter, K.K.2    Sheu, S.-S.3    Gavin, C.F.4
  • 29
    • 0023759935 scopus 로고
    • Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: Importance of the orientation of the nucleotide binding site
    • Le Quoc K., Le quoc D. Involvement of the ADP/ATP carrier in calcium-induced perturbations of the mitochondrial inner membrane permeability: importance of the orientation of the nucleotide binding site. Arch. Biochem. Biophys. 265:1988;249-257.
    • (1988) Arch. Biochem. Biophys. , vol.265 , pp. 249-257
    • Le Quoc, K.1    Le Quoc, D.2
  • 30
    • 0342940797 scopus 로고    scopus 로고
    • Fatty acids induced uncoupling of Saccharomyces cerevisiae mitochondria requires an intact ADP/ATP carrier
    • Polcic P., Sabova L., Kolarov J. Fatty acids induced uncoupling of Saccharomyces cerevisiae mitochondria requires an intact ADP/ATP carrier. FEBS Lett. 412:1997;207-210.
    • (1997) FEBS Lett. , vol.412 , pp. 207-210
    • Polcic, P.1    Sabova, L.2    Kolarov, J.3
  • 32
    • 0029830055 scopus 로고    scopus 로고
    • Photomodification of mitochondrial proteins by azido fatty acids and its effect on mitochondrial energetics. Further evidence for the role of ADP/ATP carrier in fatty-acid-mediated uncoupling
    • Schönfeld P., Jezek P., Belyaeva E.A., Borecky J., Slyshenkov V.S., Wieckowski M.R., Wojtczak L. Photomodification of mitochondrial proteins by azido fatty acids and its effect on mitochondrial energetics. Further evidence for the role of ADP/ATP carrier in fatty-acid-mediated uncoupling. Eur. J. Biochem. 240:1996;387-393.
    • (1996) Eur. J. Biochem. , vol.240 , pp. 387-393
    • Schönfeld, P.1    Jezek, P.2    Belyaeva, E.A.3    Borecky, J.4    Slyshenkov, V.S.5    Wieckowski, M.R.6    Wojtczak, L.7
  • 33
    • 0033125692 scopus 로고    scopus 로고
    • The anion-carrier mediated uncoupling effect of dicarboxylic fatty acids in liver mitochondria depends on the position of the second carboxyl group
    • Markova O.V., Bondarenko D.I., Samartsev V.N. The anion-carrier mediated uncoupling effect of dicarboxylic fatty acids in liver mitochondria depends on the position of the second carboxyl group. Biochemistry (Mosc.). 64:1999;565-570.
    • (1999) Biochemistry (Mosc.) , vol.64 , pp. 565-570
    • Markova, O.V.1    Bondarenko, D.I.2    Samartsev, V.N.3
  • 34
    • 0342614207 scopus 로고    scopus 로고
    • The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane
    • Wojtczak L., Wieckowski M.R. The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane. J. Bioenerg. Biomembr. 31:1999;447-455.
    • (1999) J. Bioenerg. Biomembr. , vol.31 , pp. 447-455
    • Wojtczak, L.1    Wieckowski, M.R.2
  • 35
    • 0032503058 scopus 로고    scopus 로고
    • Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore
    • Ruck A., Dolder M., Wallimann T., Brdickzka D. Reconstituted adenine nucleotide translocase forms a channel for small molecules comparable to the mitochondrial permeability transition pore. FEBS Lett. 426:1998;97-101.
    • (1998) FEBS Lett. , vol.426 , pp. 97-101
    • Ruck, A.1    Dolder, M.2    Wallimann, T.3    Brdickzka, D.4
  • 36
  • 37
    • 0031587822 scopus 로고    scopus 로고
    • Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals
    • Ichas F., Jouaville L.S., Mazat J.-P. Mitochondria are excitable organelles capable of generating and conveying electrical and calcium signals. Cell. 89:1997;1145-1153.
    • (1997) Cell , vol.89 , pp. 1145-1153
    • Ichas, F.1    Jouaville, L.S.2    Mazat, J.-P.3
  • 38
    • 0033540289 scopus 로고    scopus 로고
    • Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells
    • Minamikawa T., Williams D.A., Bowser D.N., Nagley P. Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells. Exp. Cell Res. 246:1999;26-37.
    • (1999) Exp. Cell Res. , vol.246 , pp. 26-37
    • Minamikawa, T.1    Williams, D.A.2    Bowser, D.N.3    Nagley, P.4
  • 39
    • 0033021780 scopus 로고    scopus 로고
    • Transient and long-lasting opening of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcium fluorescence
    • Petronilli V., Miotto G., Canton M., Brini M., Colonna R., Bernardi P., DiLisa F. Transient and long-lasting opening of the mitochondrial permeability transition pore can be monitored directly in intact cells by changes in mitochondrial calcium fluorescence. Biophys. J. 76:1999;725-734.
    • (1999) Biophys. J. , vol.76 , pp. 725-734
    • Petronilli, V.1    Miotto, G.2    Canton, M.3    Brini, M.4    Colonna, R.5    Bernardi, P.6    Dilisa, F.7
  • 40
    • 0026742968 scopus 로고
    • The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A
    • Novgorodov S.A., Gudz T.I., Milgrom Y.M., Brierley G.P. The permeability transition in heart mitochondria is regulated synergistically by ADP and cyclosporin A. J. Biol. Chem. 267:1992;16274-16282.
    • (1992) J. Biol. Chem. , vol.267 , pp. 16274-16282
    • Novgorodov, S.A.1    Gudz, T.I.2    Milgrom, Y.M.3    Brierley, G.P.4
  • 42
    • 0028075423 scopus 로고
    • Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel
    • Connern C.P., Halestrap A.P. Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel. Biochem. J. 302:1994;321-324.
    • (1994) Biochem. J. , vol.302 , pp. 321-324
    • Connern, C.P.1    Halestrap, A.P.2
  • 43
    • 0342601449 scopus 로고    scopus 로고
    • Thyroid hormone-induced expression of the ADP/ATP carrier and its effect on fatty acid induced uncoupling of oxidative phosphorylation
    • Schönfeld P., Wieckowski M.R., Wojtczak L. Thyroid hormone-induced expression of the ADP/ATP carrier and its effect on fatty acid induced uncoupling of oxidative phosphorylation. FEBS Lett. 416:1997;19-22.
    • (1997) FEBS Lett. , vol.416 , pp. 19-22
    • Schönfeld, P.1    Wieckowski, M.R.2    Wojtczak, L.3
  • 44
    • 0343473312 scopus 로고    scopus 로고
    • Hypothyroidism renders liver mitochondria resistant to the opening of membrane permeability transition pore
    • Chavez E., Franco M., Reyes-Vivas H., Zazueta C., Ramirez J., Carrillo R. Hypothyroidism renders liver mitochondria resistant to the opening of membrane permeability transition pore. Biochim. Biophys. Acta. 1407:1998;243-248.
    • (1998) Biochim. Biophys. Acta , vol.1407 , pp. 243-248
    • Chavez, E.1    Franco, M.2    Reyes-Vivas, H.3    Zazueta, C.4    Ramirez, J.5    Carrillo, R.6
  • 45
    • 0026769571 scopus 로고
    • Transcript levels for nuclear-encoded mammalian mitochondrial respiratory-chain components are regulated by thyroid hormone in an uncoordinated fashion
    • Luciakova K., Nelson B.D. Transcript levels for nuclear-encoded mammalian mitochondrial respiratory-chain components are regulated by thyroid hormone in an uncoordinated fashion. Eur. J. Biochem. 207:1992;247-251.
    • (1992) Eur. J. Biochem. , vol.207 , pp. 247-251
    • Luciakova, K.1    Nelson, B.D.2
  • 46
    • 0025970029 scopus 로고
    • Functional relationship of thyroid hormone-induced lipogenesis, lipolysis and thermogenesis in the rat
    • Oppenheimer T.H., Schwartz H.L., Lane J.T., Thompson M.P. Functional relationship of thyroid hormone-induced lipogenesis, lipolysis and thermogenesis in the rat. J. Clin. Invest. 87:1991;125-132.
    • (1991) J. Clin. Invest. , vol.87 , pp. 125-132
    • Oppenheimer, T.H.1    Schwartz, H.L.2    Lane, J.T.3    Thompson, M.P.4
  • 47
    • 0030773514 scopus 로고    scopus 로고
    • Sensitization to insulin induced by β,β′-methyl-substituted hexadecanedioic acid (MEDICA 16) in obese Zucker rats in vivo
    • Mayorek N., Kalderon B., Itach E., Bar-Tana J. Sensitization to insulin induced by β,β′-methyl-substituted hexadecanedioic acid (MEDICA 16) in obese Zucker rats in vivo. Diabetes. 46:1997;1958-1964.
    • (1997) Diabetes , vol.46 , pp. 1958-1964
    • Mayorek, N.1    Kalderon, B.2    Itach, E.3    Bar-Tana, J.4
  • 48
    • 0026713543 scopus 로고
    • Tissue selective modulation of redox and phosphate potentials by β,β′-methyl-substituted hexadecanedioic acid
    • Kalderon B., Hertz R., Bar-Tana J. Tissue selective modulation of redox and phosphate potentials by β,β′-methyl-substituted hexadecanedioic acid. Endocrinology. 131:1992;1629-1635.
    • (1992) Endocrinology , vol.131 , pp. 1629-1635
    • Kalderon, B.1    Hertz, R.2    Bar-Tana, J.3


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