메뉴 건너뛰기




Volumn 53, Issue 4, 2001, Pages 273-277

Distinct function of Th1 and Th2 type delayed type hypersensitivity: Protective and pathological reactions to chlamydial infection

Author keywords

Chlamydia; Delayed hypersensitivity; Knockout; Th1 Th2

Indexed keywords

PATHOLOGY;

EID: 0035873178     PISSN: 1059910X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jemt.1093     Document Type: Article
Times cited : (17)

References (57)
  • 1
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, AK, Murphy KM, Sher A. 1996a. Functional diversity of helper T lymphocytes. Nature 383:787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 2
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas AK, Murphy KM, Sher A. 1996b. Functional diversity of helper T lymphocytes. Nature 383:787-793.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 3
    • 0027438181 scopus 로고
    • The influence of local antichlamydial antibody on the acquisition and persistence of human ocular chlamydial infection: IgG antibodies are not protective
    • Bailey RL, Kajbaf M, Whittle HC, Ward ME, Mabey DC. 1993. The influence of local antichlamydial antibody on the acquisition and persistence of human ocular chlamydial infection: IgG antibodies are not protective. Epidemiol Infect 111:315-324.
    • (1993) Epidemiol Infect , vol.111 , pp. 315-324
    • Bailey, R.L.1    Kajbaf, M.2    Whittle, H.C.3    Ward, M.E.4    Mabey, D.C.5
  • 4
    • 0028032538 scopus 로고
    • Chlamydia trachomatis antigens: Role in immunity and pathogenesis
    • Brunham RC, Peeling RW. 1994. Chlamydia trachomatis antigens: role in immunity and pathogenesis. Infect Agents Dis 3:218-233.
    • (1994) Infect Agents Dis , vol.3 , pp. 218-233
    • Brunham, R.C.1    Peeling, R.W.2
  • 6
    • 0028967628 scopus 로고
    • Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis
    • Cain TK, Rank RG. 1995. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect Immun 63:1784-1789.
    • (1995) Infect Immun , vol.63 , pp. 1784-1789
    • Cain, T.K.1    Rank, R.G.2
  • 7
    • 0033579928 scopus 로고    scopus 로고
    • Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection
    • Cerwenka A, Morgan TM, Harmsen AG, Dutton RW. 1999. Migration kinetics and final destination of type 1 and type 2 CD8 effector cells predict protection against pulmonary virus infection. J Exp Med 189:423-434.
    • (1999) J Exp Med , vol.189 , pp. 423-434
    • Cerwenka, A.1    Morgan, T.M.2    Harmsen, A.G.3    Dutton, R.W.4
  • 8
    • 0026607159 scopus 로고
    • Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma mansoni-infected mice while selectively inhibiting T cell IL-5 production
    • Cheever AW, Finkelman FD, Caspar P, Heiny S, Macedonia JG, Sher A. 1992. Treatment with anti-IL-2 antibodies reduces hepatic pathology and eosinophilia in Schistosoma mansoni-infected mice while selectively inhibiting T cell IL-5 production. J Immunol 148: 3244-3248.
    • (1992) J Immunol , vol.148 , pp. 3244-3248
    • Cheever, A.W.1    Finkelman, F.D.2    Caspar, P.3    Heiny, S.4    Macedonia, J.G.5    Sher, A.6
  • 9
    • 0028363023 scopus 로고
    • Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis
    • Cheever AW, Williams ME, Wynn TA, Finkelman FD, Seder RA, Cox TM, Hieny S, Casper P, Sher A. 1994. Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis. J Immunol 153:753-759.
    • (1994) J Immunol , vol.153 , pp. 753-759
    • Cheever, A.W.1    Williams, M.E.2    Wynn, T.A.3    Finkelman, F.D.4    Seder, R.A.5    Cox, T.M.6    Hieny, S.7    Casper, P.8    Sher, A.9
  • 10
    • 0023269443 scopus 로고
    • Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones
    • Cher DJ, Mosmann TR. 1987. Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones. J Immunol 138:3688-3696.
    • (1987) J Immunol , vol.138 , pp. 3688-3696
    • Cher, D.J.1    Mosmann, T.R.2
  • 12
    • 0030988438 scopus 로고    scopus 로고
    • Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice
    • Cotter TW, Ramsey KH, Miranpuri GS, Poulsen CE, Byrne GI. 1997. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect Immun 65:2145-2152.
    • (1997) Infect Immun , vol.65 , pp. 2145-2152
    • Cotter, T.W.1    Ramsey, K.H.2    Miranpuri, G.S.3    Poulsen, C.E.4    Byrne, G.I.5
  • 14
    • 0024433227 scopus 로고
    • The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones
    • Fong TAT, Mosmann TR. 1989. The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. J Immunol 143: 2887-2894.
    • (1989) J Immunol , vol.143 , pp. 2887-2894
    • Fong, T.A.T.1    Mosmann, T.R.2
  • 15
    • 0141512943 scopus 로고
    • The histopathology of murine pneumonitis infection and the growth of the virus in the mouse lung
    • Gogolak FM. 1953. The histopathology of murine pneumonitis infection and the growth of the virus in the mouse lung. J Infect Dis 92:254-260.
    • (1953) J Infect Dis , vol.92 , pp. 254-260
    • Gogolak, F.M.1
  • 16
    • 0025147386 scopus 로고
    • Cultured epidermal langerhans cells activate effector T cells for contact sensitivity
    • Hauser C. 1990. Cultured epidermal Langerhans cells activate effector T cells for contact sensitivity. J Invest Dermatol 95:436-442.
    • (1990) J Invest Dermatol , vol.95 , pp. 436-442
    • Hauser, C.1
  • 17
    • 0027524749 scopus 로고
    • Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens
    • Holland MJ, Bailey RL, Hayes LJ, Whittle HC, Mabey DC. 1993. Conjunctival scarring in trachoma is associated with depressed cell-mediated immune responses to chlamydial antigens. J Infect Dis 168:1528-1531.
    • (1993) J Infect Dis , vol.168 , pp. 1528-1531
    • Holland, M.J.1    Bailey, R.L.2    Hayes, L.J.3    Whittle, H.C.4    Mabey, D.C.5
  • 18
    • 0029846656 scopus 로고    scopus 로고
    • T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring
    • Holland MJ, Bailey RL, Conway DJ, Culley F, Miranpuri G, Byme GI, Whittle HC, Mabey DC. 1996. T helper type-1 (Th1)/Th2 profiles of peripheral blood mononuclear cells (PBMC); responses to antigens of Chlamydia trachomatis in subjects with severe trachomatous scarring. Clin Exp Immunol 105:429-435.
    • (1996) Clin Exp Immunol , vol.105 , pp. 429-435
    • Holland, M.J.1    Bailey, R.L.2    Conway, D.J.3    Culley, F.4    Miranpuri, G.5    Byme, G.I.6    Whittle, H.C.7    Mabey, D.C.8
  • 19
    • 0018763376 scopus 로고
    • Growth and effect of chlamydiae in human and bovine oviduct organ cultures
    • Hutchinson GR, Taylor-Robinson D, Dourmashkin RR. 1979. Growth and effect of chlamydiae in human and bovine oviduct organ cultures. Br J Vener Dis 55:194-202.
    • (1979) Br J Vener Dis , vol.55 , pp. 194-202
    • Hutchinson, G.R.1    Taylor-Robinson, D.2    Dourmashkin, R.R.3
  • 20
    • 0028068426 scopus 로고
    • An in vitro model for immune control of chlamydial growth in polarized epithelial cells
    • Igietseme JU, Wyrick PB, Goyeau D, Rank RG. 1994. An in vitro model for immune control of chlamydial growth in polarized epithelial cells. Infect Immun 62:3528-3535.
    • (1994) Infect Immun , vol.62 , pp. 3528-3535
    • Igietseme, J.U.1    Wyrick, P.B.2    Goyeau, D.3    Rank, R.G.4
  • 21
    • 0029934121 scopus 로고    scopus 로고
    • Integrin-mediated epithelial-T cell interaction enhances nitric oxide production and increased intracellular inhibition of Chlamydia
    • Igietseme JU, Uriri IM, Hawkins R, Rank RG. 1996. Integrin-mediated epithelial-T cell interaction enhances nitric oxide production and increased intracellular inhibition of Chlamydia. J Leukoc Biol 59:656-662.
    • (1996) J Leukoc Biol , vol.59 , pp. 656-662
    • Igietseme, J.U.1    Uriri, I.M.2    Hawkins, R.3    Rank, R.G.4
  • 22
    • 0031470928 scopus 로고    scopus 로고
    • Studies in knockout mice reveal that anti-chlamydial protection requires TH1 cells producing IFN-gamma: Is this true for humans?
    • Johansson M, Schon K, Ward M, Lycke N. 1997a. Studies in knockout mice reveal that anti-chlamydial protection requires TH1 cells producing IFN-gamma: is this true for humans? Scandinavian J Immunol 46:546-552.
    • (1997) Scandinavian J Immunol , vol.46 , pp. 546-552
    • Johansson, M.1    Schon, K.2    Ward, M.3    Lycke, N.4
  • 23
    • 0031020913 scopus 로고    scopus 로고
    • Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response
    • Johansson M, Schon K, Ward M, Lycke N. 1997b. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma Interferon receptor-deficient mice despite a strong local immunoglobulin A response. Infect Immun 65:1032-1044.
    • (1997) Infect Immun , vol.65 , pp. 1032-1044
    • Johansson, M.1    Schon, K.2    Ward, M.3    Lycke, N.4
  • 24
    • 0030773745 scopus 로고    scopus 로고
    • Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis
    • Kelly KA, Rank RG. 1997. Identification of homing receptors that mediate the recruitment of CD4 T cells to the genital tract following intravaginal infection with Chlamydia trachomatis. Infect Immun 65:5198-5208.
    • (1997) Infect Immun , vol.65 , pp. 5198-5208
    • Kelly, K.A.1    Rank, R.G.2
  • 25
    • 0029805938 scopus 로고    scopus 로고
    • Initial route of antigen administration alters the T-cell cytokine profile produced in response to the mouse pneumonitis biovar of Chlamydia trachomatis following genital infection
    • Kelly KA, Robinson EA, Rank RG. 1996. Initial route of antigen administration alters the T-cell cytokine profile produced in response to the mouse pneumonitis biovar of Chlamydia trachomatis following genital infection. Infect Immun 64:4976-4983.
    • (1996) Infect Immun , vol.64 , pp. 4976-4983
    • Kelly, K.A.1    Robinson, E.A.2    Rank, R.G.3
  • 26
    • 0026047282 scopus 로고
    • Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis
    • Landers DV, Erlich K, Sung M, Schatcher J. 1991. Role of L3T4-bearing T-cell populations in experimental murine chlamydial salpingitis. Infect Immun 59:3774-3777.
    • (1991) Infect Immun , vol.59 , pp. 3774-3777
    • Landers, D.V.1    Erlich, K.2    Sung, M.3    Schatcher, J.4
  • 27
    • 0031137015 scopus 로고    scopus 로고
    • CDSTc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions
    • Li L, Sad S, Kagi D, Mosmann TR. 1997. CDSTc1 and Tc2 cells secrete distinct cytokine patterns in vitro and in vivo but induce similar inflammatory reactions. J Immunol 158:4152-4161.
    • (1997) J Immunol , vol.158 , pp. 4152-4161
    • Li, L.1    Sad, S.2    Kagi, D.3    Mosmann, T.R.4
  • 28
    • 0030191407 scopus 로고    scopus 로고
    • Immunity to Chlamydia trachomatis: Lesson from a Gambian village
    • Mailey DCW, Bailey RL. 1996. Immunity to Chlamydia trachomatis: lesson from a Gambian village. J Med Microbiol 45:1-2.
    • (1996) J Med Microbiol , vol.45 , pp. 1-2
    • Mailey, D.C.W.1    Bailey, R.L.2
  • 29
    • 0030248686 scopus 로고    scopus 로고
    • Tissue-specific migration of lymphocytes: A key role for Th1 and Th2 cells?
    • Meeusen ENT, Premier RR, Bandon MR. 1996. Tissue-specific migration of lymphocytes: a key role for Th1 and Th2 cells? Immunol Today 17:421-424.
    • (1996) Immunol Today , vol.17 , pp. 421-424
    • Meeusen, E.N.T.1    Premier, R.R.2    Bandon, M.R.3
  • 31
    • 0001000640 scopus 로고
    • Isolation from normal mice of a pneumotropic virus which forms elementary bodies
    • Nigg C, Eaton MD. 1944. Isolation from normal mice of a pneumotropic virus which forms elementary bodies. J Exp Med 79:497-509.
    • (1944) J Exp Med , vol.79 , pp. 497-509
    • Nigg, C.1    Eaton, M.D.2
  • 32
    • 0022154754 scopus 로고
    • Immunopathology and histopathology of experimental chlamydial salpingitis
    • Patton DL. 1985. Immunopathology and histopathology of experimental chlamydial salpingitis. Rev Infect Dis 7:746-753.
    • (1985) Rev Infect Dis , vol.7 , pp. 746-753
    • Patton, D.L.1
  • 33
    • 0026060650 scopus 로고
    • Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni
    • Pearce EJ, Caspar P, Crzych JM, Lewis FA, Sher A. 1991. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J Exp Med 173:159-166.
    • (1991) J Exp Med , vol.173 , pp. 159-166
    • Pearce, E.J.1    Caspar, P.2    Crzych, J.M.3    Lewis, F.A.4    Sher, A.5
  • 34
    • 0031112653 scopus 로고    scopus 로고
    • Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways
    • Perry LL, Feilzer K, Caldwell HD. 1997. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-gamma-dependent and -independent pathways. J Immunol 158:3344-3352.
    • (1997) J Immunol , vol.158 , pp. 3344-3352
    • Perry, L.L.1    Feilzer, K.2    Caldwell, H.D.3
  • 35
    • 0032521028 scopus 로고    scopus 로고
    • Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice
    • Perry LL, Feilzer K, Portis JL, Caldwell HD. 1998. Distinct homing pathways direct T lymphocytes to the genital and intestinal mucosae in Chlamydia-infected mice. J Immunol 160:2905-2914.
    • (1998) J Immunol , vol.160 , pp. 2905-2914
    • Perry, L.L.1    Feilzer, K.2    Portis, J.L.3    Caldwell, H.D.4
  • 36
    • 0026557277 scopus 로고
    • Evolution of the human immunodeficiency virus epidemic among patients attending sexually transmitted disease clinics: A decade of experience
    • Quinn TC, Groseclose SL, Spence M, Provost V, Hook EW. 1992. Evolution of the human immunodeficiency virus epidemic among patients attending sexually transmitted disease clinics: a decade of experience. J Infect Dis 165:541-544.
    • (1992) J Infect Dis , vol.165 , pp. 541-544
    • Quinn, T.C.1    Groseclose, S.L.2    Spence, M.3    Provost, V.4    Hook, E.W.5
  • 37
    • 0020505639 scopus 로고
    • Effect of antithymocyte serum on the course of chlamydial genital infection in female guinea pigs
    • Rank RG, Barron AL. 1983. Effect of antithymocyte serum on the course of chlamydial genital infection in female guinea pigs. Infect Immun 41:876-879.
    • (1983) Infect Immun , vol.41 , pp. 876-879
    • Rank, R.G.1    Barron, A.L.2
  • 38
    • 0021929290 scopus 로고
    • Chronic chlamydial genital infection in congenitally athymic nude mice
    • Rank RG, Soerberg LSF, Barron AL. 1985. Chronic chlamydial genital infection in congenitally athymic nude mice. Infect Immun 48: 847-849.
    • (1985) Infect Immun , vol.48 , pp. 847-849
    • Rank, R.G.1    Soerberg, L.S.F.2    Barron, A.L.3
  • 39
    • 0024561162 scopus 로고
    • Role of cell-mediated immunity in the resolution of secondary chlamydial genital infection in guinea pigs infected with the agent of guinea pig inclusion conjunctivitis
    • Rank RG, Soderberg LS, Sanders MM, Batteiger BE. 1989. Role of cell-mediated immunity in the resolution of secondary chlamydial genital infection in guinea pigs infected with the agent of guinea pig inclusion conjunctivitis. Infect Immun 57:706-710.
    • (1989) Infect Immun , vol.57 , pp. 706-710
    • Rank, R.G.1    Soderberg, L.S.2    Sanders, M.M.3    Batteiger, B.E.4
  • 40
    • 0028802076 scopus 로고
    • Increased incidence of oviduct pathology in the guinea pig after repeat vaginal inoculation with the chlamydial agent of guinea pig inclusion conjunctivitis
    • Rank RG, Sanders MM, Patton DL. 1995. Increased incidence of oviduct pathology in the guinea pig after repeat vaginal inoculation with the chlamydial agent of guinea pig inclusion conjunctivitis. Sex Transm Dis 22:48-54.
    • (1995) Sex Transm Dis , vol.22 , pp. 48-54
    • Rank, R.G.1    Sanders, M.M.2    Patton, D.L.3
  • 41
    • 0018146351 scopus 로고
    • Cell-mediated immune responses in owl monkeys (Aotus trivirgatus) with trachoma to soluble antigens of Chlamydia trachomatis
    • Sacks DL, Todd WJ, Macdonald AB. 1978. Cell-mediated immune responses in owl monkeys (Aotus trivirgatus) with trachoma to soluble antigens of Chlamydia trachomatis. Clin Exp Immunol 33: 57-64.
    • (1978) Clin Exp Immunol , vol.33 , pp. 57-64
    • Sacks, D.L.1    Todd, W.J.2    Macdonald, A.B.3
  • 42
    • 0029162732 scopus 로고
    • CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract
    • Su H, Caldwell H. 1995. CD4+ T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect Immun 63:3302-3308.
    • (1995) Infect Immun , vol.63 , pp. 3302-3308
    • Su, H.1    Caldwell, H.2
  • 44
    • 0025364578 scopus 로고
    • Severity of salpingitis in mice after primary and repeated inoculation with a human strain of Chlamydia trachomatis
    • Tuffrey M, Alexander F, Taylor-Robinson D. 1990. Severity of salpingitis in mice after primary and repeated inoculation with a human strain of Chlamydia trachomatis. J Exp Pathol (Oxford) 71:403-410.
    • (1990) J Exp Pathol (Oxford) , vol.71 , pp. 403-410
    • Tuffrey, M.1    Alexander, F.2    Taylor-Robinson, D.3
  • 45
    • 0032751041 scopus 로고    scopus 로고
    • Interferon-γ knockout mice show Th2 associated delayed type hypersensitivity that fails to clear Chlamydia trachomatis mouse pneumonitis infection
    • Wang S, Fan Y, Brunham RC, Yang X. 1999. Interferon-γ knockout mice show Th2 associated delayed type hypersensitivity that fails to clear Chlamydia trachomatis mouse pneumonitis infection. Eur J Immunol 29:3782-3792.
    • (1999) Eur J Immunol , vol.29 , pp. 3782-3792
    • Wang, S.1    Fan, Y.2    Brunham, R.C.3    Yang, X.4
  • 46
    • 0029585758 scopus 로고
    • The immunobiology and immunopathology of chlamydial infections
    • Ward ME. 1995. The immunobiology and immunopathology of chlamydial infections. APMIS 103:769-796.
    • (1995) APMIS , vol.103 , pp. 769-796
    • Ward, M.E.1
  • 47
    • 0343888429 scopus 로고
    • Ocular delayed hypersensitivity: A pathogenetic mechanism of chlamydial-conjunctivitis in guinea pigs
    • Wtkins NG, Hodlow WJ, Moos AB, Caldwell HD. 1986. Ocular delayed hypersensitivity: a pathogenetic mechanism of chlamydial-conjunctivitis in guinea pigs. Proc Natl Acad Sci USA 83:7480-7484.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 7480-7484
    • Wtkins, N.G.1    Hodlow, W.J.2    Moos, A.B.3    Caldwell, H.D.4
  • 48
    • 0015875020 scopus 로고
    • Immunity to chlamydial infections of the eye. 3. Presence and duration of delayed hypersensitivity to guinea pig inclusion conjunctivitis
    • Watson RR, MacDonald AB, Murray ES, Modabber FZ. 1973. Immunity to chlamydial infections of the eye. 3. Presence and duration of delayed hypersensitivity to guinea pig inclusion conjunctivitis. J Immunol 111:618-623.
    • (1973) J Immunol , vol.111 , pp. 618-623
    • Watson, R.R.1    MacDonald, A.B.2    Murray, E.S.3    Modabber, F.Z.4
  • 50
    • 0029166483 scopus 로고
    • Cytokine regulation of granuloma formation in schistosomiasis
    • Wynn TA, Cheever AW. 1995. Cytokine regulation of granuloma formation in schistosomiasis. Curr Opin Immunol 7:505-511.
    • (1995) Curr Opin Immunol , vol.7 , pp. 505-511
    • Wynn, T.A.1    Cheever, A.W.2
  • 51
    • 0028231754 scopus 로고
    • Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology
    • Wynn TA, Eltoum I, Oswald IP, Cheever AW, Sher A. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J Exp Med 179:1551-1561.
    • (1994) J Exp Med , vol.179 , pp. 1551-1561
    • Wynn, T.A.1    Eltoum, I.2    Oswald, I.P.3    Cheever, A.W.4    Sher, A.5
  • 53
    • 0031976523 scopus 로고    scopus 로고
    • T lymphocyte immunity in host defence against Chlamydia trachmatis and implication for vaccine development
    • Yang X, Brunham RC. 1998. T lymphocyte immunity in host defence against Chlamydia trachmatis and implication for vaccine development. Can J Infect Dis 9:99-109.
    • (1998) Can J Infect Dis , vol.9 , pp. 99-109
    • Yang, X.1    Brunham, R.C.2
  • 54
    • 0032969562 scopus 로고    scopus 로고
    • In pursuit of a human chlamydial vaccine
    • Yang X, Brunham RC. 1999. In pursuit of a human chlamydial vaccine. Curr Opin Infect Dis 12:47-52.
    • (1999) Curr Opin Infect Dis , vol.12 , pp. 47-52
    • Yang, X.1    Brunham, R.C.2
  • 55
    • 0029976591 scopus 로고    scopus 로고
    • Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection
    • Yang X, HayGlass KT, Brunham RC. 1996. Genetically determined differences in IL-10 and IFN-gamma responses correlate with clearance of Chlamydia trachomatis mouse pneumonitis infection. J Immunol 156:4338-4344.
    • (1996) J Immunol , vol.156 , pp. 4338-4344
    • Yang, X.1    HayGlass, K.T.2    Brunham, R.C.3
  • 56
    • 0031831854 scopus 로고    scopus 로고
    • Different roles are played by αβ and γδ T cell in acquired immunity to murine Chlamydia trachomatis pulmonary infection
    • Yang X, HayGlass KT, Brunham RC. 1998. Different roles are played by αβ and γδ T cell in acquired immunity to murine Chlamydia trachomatis pulmonary infection. Immunology 94:469-475.
    • (1998) Immunology , vol.94 , pp. 469-475
    • Yang, X.1    HayGlass, K.T.2    Brunham, R.C.3
  • 57
    • 0033556174 scopus 로고    scopus 로고
    • IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection
    • Yang X, Gartner J, Zhu L, Wang S, Brunham RC. 1999. IL-10 gene knockout mice show enhanced Th1-like protective immunity and absent granuloma formation following Chlamydia trachomatis lung infection. J Immunol 162:1010-1017.
    • (1999) J Immunol , vol.162 , pp. 1010-1017
    • Yang, X.1    Gartner, J.2    Zhu, L.3    Wang, S.4    Brunham, R.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.