Monoclonal antibody 8H9 targets a novel cell surface antigen expressed by a wide spectrum of human solid tumors

Cancer Research

Volumn 61, Issue 10, 2001, Pages 4048-4054

  Modak, S ^a   Kramer, K ^a   Gultekin, S H ^a   Guo, H F ^a   Cheung, N K V ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; TUMOR ANTIGEN;

ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; BRAIN TUMOR; CELL COMPARTMENTALIZATION; GLYCOSYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; PRIORITY JOURNAL; PROGNOSIS; SOLID TUMOR; TARGET CELL; TUMOR VOLUME;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, NEOPLASM; ANTIGENS, SURFACE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMMUNOGLOBULIN G; IMMUNOHISTOCHEMISTRY; MACACA FASCICULARIS; MICE; MICE, INBRED BALB C; NEOPLASMS; NEUROBLASTOMA; PRECIPITIN TESTS; TUMOR CELLS, CULTURED;

EID: 0035872404     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Anti-GD2 antibody treatment of minimal residual stage 4 neuroblastoma diagnosed at more than 1 year of age
2. Phase I trial of a human-mouse chimeric antidisialoganglioside monoclonal antibody ch14.18 in patients with refractory neuroblastoma and osteosarcoma
3. Sequential targeted therapy for acute promyelocytic leukemia with all-trans-retinoic acid and anti-CD33 monoclonal antibody M195
4. Combination chemotherapy with trastuzumab (Herceptin) and cisplatin for chemoresistant metastatic breast cancer: Evidence for receptor-enhanced chemosensitivity
5. Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy
6. Immunohistochemical analysis of neural cell adhesion molecules. Differential expression in small round cell tumors of childhood and adolescence
7. Ganglioside antigens expressed by human cancer cells
8. CD44 expression in astrocytic tumors
9. 125I-labeled antiepidermal growth factor receptor-vIII single-chain Fv exhibits specific and high-level targeting of glioma xenografts
10. Radioimmunolocalization of human brain tumors. Biodistribution of radiolabelled monoclonal antibody UJ13A
11. 131I-monoclonal antibody: Feasibility, pharmacokinetics, and dosimetry
12. Induction of antitumor cytotoxic T lymphocytes in normal humans using primary cultures and synthetic peptide epitopes
13. Iodine-131-labeled anti-tenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: Phase I trial results
14. 131I radioconjugated antibodies for the locoregional radioimmunotherapy of high-grade malignant glioma-Phase I and II study
15. D2 specific monoclonal antibody in human osteogenic sarcoma xenografts
16. Decay accelerating factor (CD55): A target for cancer vaccines?
17. New monoclonal antibodies specific for human sarcomas
18. Immunohistochemical profile of monoclonal antibody O13 that recognizes glycoprotein 930/32MIC2 and is useful in diagnosing Ewing's sarcoma and peripheral neuroepithelioma
19. Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood
20. The use of a monoclonal anti-idiotype antibody to study the biology of human B-cell lymphoma
21. Monoclonal antibodies to a glycolipid antigen on human neuroblastoma cells
22. Prognostic value of TrkA protein detection my monoclonal antibody 5C3 in neuroblastoma
23. Production and characterization of a monoclonal antibody that binds Reed-Sternberg cells
24. Definition of a Thy-1 determinant on human neuroblastoma, glioma, sarcoma, and teratoma cells with a monoclonal antibody
25. Expression of CD44 splice variants in human primary brain tumors
26. Lactotetraose series ganglioside 3′,6′-isoLD1 in tumors of central nervous and other systems in vitro and in vivo
27. Rhabdomyosarcoma: Biology and treatment
28. A monoclonal antibody with selective immunoreactivity for neuroblastoma and rhabdomyosarcoma
29. Monoclonal antibodies against EGFRvIII are tumor specific and react with breast and lung carcinomas and malignant gliomas
30. Monoclonal antibody ONS-21 recognizes integrin α3 in gliomas and gliomas and medulloblastomas
31. Characterization of a new mouse monoclonal antibody (ONS-M21) reactive with both medulloblastomas and gliomas
32. Human glioma-specific antigens detected by monoclonal antibodies
33. Monoclonal antibody against human glioblastoma multiforme (U-87Mg) immunoprecipitates a protein of monoclonal mass 38 KDa and inhibits tumor growth in nude mice
34. Monoclonal antibody against ependymoma-derived cell line
35. Development of a method to measure kinetics of radiolabeled monoclonal antibody in human tumour with applications to microdosimetry: Positron emission tomography studies of iodine-124-labeled 3F8 monoclonal antibody in glioma
36. Platelet-derived growth factor b is induced during tumor development and up-regulated during tumor progression in endothelial cells in human gliomas
37. Expression of 300-kilodalton intermediate filament-associated protein distinguishes human glioma cells from normal astrocytes
38. Phase I studies of treatment of malignant gliomas and neoplastic meningitis with 131I radiolabeled monoclonal antibodies antitenascin 81C6 and antichondroitin proteoglycan sulfate Mel-14 (ab′)2-a preliminary report
39. A pilot pharmacokinetic and immunoscintigraphic study with the technetium-99m-labeled monoclonal antibody BC-1 directed against oncofetal fibronectin in patients with brain tumors