Participation of manganese-superoxide dismutase in the neuroprotection exerted by copper sulfate against 1-methyl 4-phenylpyridinium neurotoxicity

Brain Research Bulletin

Volumn 55, Issue 2, 2001, Pages 277-279

  Alcaraz Zubeldia, M ^a   Montes, S ^a   Rios C ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

Author keywords

Antioxidant defense; Metals; Oxidative stress; Parkinson's disease

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANTIOXIDANT; COPPER SULFATE; FREE RADICAL; MANGANESE SUPEROXIDE DISMUTASE;

ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL;

1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; ANTIOXIDANTS; BRAIN; COPPER SULFATE; DRUG ADMINISTRATION SCHEDULE; LIPID PEROXIDATION; MALE; MICE; MICE, INBRED C57BL; MPTP POISONING; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; OXIDATIVE STRESS; SULFATES; SUPEROXIDE DISMUTASE;

EID: 0035872394     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(01)00513-5     Document Type: Conference Paper

References (19)

1. Neuroprotective effect of acute and chronic administration of copper (II) sulfate against MPP+ neurotoxicity in mice
2. Oxidants, antioxidants and the degenerative diseases of aging
3. Wilson disease and Menkes disease: New handles on heavy metal transport
4. 3H-DOPA in various regions of the brain
5. 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent supoeroxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
6. MPTP produces differential oxidative stress and antioxidative responses in the nigrostriatal and mesolimbic dopaminergic pathways
7. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
8. Nutrition and metabolism of the trace elements
9. Copper biochemistry and molecular biology
10. Neurochemical roles of copper as an antioxidant or prooxidant
11. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropiridine (MPTP)-induced dopaminergic neurotoxicity
12. Depletion of copper and manganese in brain after MPTP treatment of mice
13. Increased striatal lipid peroxidation after intracerebroventricular MPP+ administration to mice
14. Copper supplementation blocks 1-methyl-4-phenylpyridinium neurotoxicity in mice
15. Differential decrease of copper content and of copper binding to superoxide dismutase in liver, heart and brain of copper deficient rats
16. Oxidative stress in neurodegenerative diseases
17. Radiation protection and radiation recovery with essential metalloelement chelates
18. Effects of over and under expression of Cu/Zn-superoxide dismutase on the toxicity of glutamate analogs in transgenic mouse striatum
19. Regulation of manganese superoxide dismutase by lipopolysaccharide, interleukin-I and tumor necrosis factor