Determination of interaction kinetic constants for HIV-1 protease inhibitors using optical biosensor technology

Analytical Biochemistry

Volumn 291, Issue 2, 2001, Pages 207-218

  Markgren, Per Olof ^a   Lindgren, Maria T ^a   Gertow, Karl ^a   Karlsson, Robert ^b   Hämäläinen, Markku ^b   Danielson, U Helena ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b BIACORE AB   (Sweden)

Author keywords

Affinity; Association; Biacore; Binding; Biosensor; Dissociation; HIV; Indinavir; Inhibition; Inhibitor; Interaction; Mass transport; Nelfinavir; Protease; Ritonavir; Saquinavir; Surface plasmon resonance (SPR)

Indexed keywords

BIOSENSORS; DISSOCIATION; ENZYME INHIBITION; ENZYMES; MASS TRANSFER; RATE CONSTANTS; SURFACE PLASMON RESONANCE;

AFFINITY; BIACORE; BINDING; INDINAVIR; INHIBITOR; INTERACTION; NELFINAVIR; PROTEASE; RITONAVIR; SAQUINAVIR;

ASSOCIATION REACTIONS;

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; INDINAVIR; NELFINAVIR; PROTEINASE; PROTEINASE INHIBITOR; RITONAVIR; SAQUINAVIR; SUCCINIMIDE;

ARTICLE; BINDING AFFINITY; BIOSENSOR; DISSOCIATION; ENZYME BINDING; ENZYME INHIBITION; HUMAN IMMUNODEFICIENCY VIRUS 1; HYPOTHESIS; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; SURFACE PLASMON RESONANCE;

HUMAN IMMUNODEFICIENCY VIRUS 1; TRIXIS;

EID: 0035871240     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.2001.5025     Document Type: Article

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