In utero transplantation of fetal liver cells in the mucopolysaccharidosis type VII mouse results in low-level chimerism, but overexpression of β-glucuronidase can delay onset of clinical signs

Blood

Volumn 97, Issue 6, 2001, Pages 1625-1634

  Casal, Margret L ^a   Wolfe, John H ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCURONIDASE; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY AFFINITY; ARTICLE; CHIMERA; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; ENZYME DEFICIENCY; FETUS; GENE OVEREXPRESSION; GENE TRANSFER; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HOST CELL; MOUSE; MUCOPOLYSACCHARIDOSIS TYPE 7; NONHUMAN; PRIORITY JOURNAL; RETROVIRUS; STEM CELL; TRANSGENE;

EID: 0035869531     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V97.6.1625     Document Type: Article

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