Variable immunodominance hierarchies for H2-M3-restricted N-formyl peptides following bacterial infection

Journal of Immunology

Volumn 166, Issue 2, 2001, Pages 1132-1140

  Kerksiek, K M ^a   Busch, D H ^a   Pamer, E G ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; FORMYLMETHIONINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL INFECTION; CONTROLLED STUDY; CROSS REACTION; FEMALE; IMMUNE RESPONSE; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0035863720     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.166.2.1132     Document Type: Article

References (34)

1. The molecular biology of leukocyte chemoattractant receptors
2. Impaired antibacterial host defense in mice lacking the N-formylpeptide receptor
3. H2-M3 a full service class Ib histocompatibility antigen
4. Specialized functions of MHC class I molecules. 1. An N-formyl peptide receptor is required for construction of the class I antigen Mta
5. Specialized functions of major histocompatibility complex class 1 molecules. II. Hint binds N-formylated peptides of mitochondrial and prokaryotic origin
6. Peptide presentation by the MHC class Ib molecule, H2-M3
7. Identification of an H2-M3-restricted Listeria epitope: Implications for antigen presentation by M3
8. The alloreactive T cell response against the class Ib molecule H2-M3 is specific for high affinity peptides
9. Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera
10. The majority of H2-M3 is retained intracellularly in a peptide-receptive state and traffics to the cell surface in the presence of N-formylated peptides
11. Positive selection of an H2-M3 restricted T cell receptor
12. The selection of M3-restricted T cells is dependent on M3 expression and presentation of N-formylated peptides in the thymus
13. + cytolytic T lymphocytes from mice infected with the intracellular bacterium Listeria monocytogenes
14. Metabolic requirements for macrophage presentation of Listeria monocytogenes to immune CD8 cells
15. + T cells with cytolytic and protective activity
16. MHC-unrestricted transfer of antilisterial immunity by freshly isolated immune CD8 spleen cells
17. Specialized role for a routine class I-b MHC molecule in prokaryotic host defenses
18. H2-M3 presents a Listeria monocytogenes peptide to cytotoxic T lymphocytes
19. A Listeria monocytogenes pentapeptide is presented to cytolytic T lymphocytes by the H2-M3 MHC class Ib molecule
20. H2-M3 restricted presentation of a Listeria-derived leader peptide
21. H2-M3 restricted T cells: Rapid effector function during primary bacterial infection and diminished memory responses
22. CTL responses to H2-M3-restricted Listeria epitopes
23. H2M3wt-restricted, Listeria monocytogenes-immune CD8 T cells respond to multiple formylated peptides and to a variety of Gram-positive and Gram-negative bacteria
24. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
25. Coordinate regulation of complex T cell populations responding to bacterial infection
26. MHC class I/peptide stability: Implications for immunodominance, in vitro proliferation and diversity of responding CTL
27. Killer cell assays
28. Unresponsiveness to a self-peptide of mouse lysozyme owing to hindrance of T cell receptor-major histocompatibility complex/peptide interaction caused by flanking epitopic residues
29. Nonclassical binding of formylated peptide in crystal structure of the MHC class Ib molecule H2-M3
30. CD8 T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity
31. Requirement of endogenous interferon-γ production for resolution of Listeria monocytogenes infection
32. Specific immunity to Listeria monocytogenes in the absence of IFN-γ
33. Production of tumor necrosis factor during murine listeriosis
34. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection