Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway

Biochemical Journal

Volumn 353, Issue 2, 2001, Pages 267-273

  De Los Pinos, E ^a   Fernandez De Mattos, S ^a   Joaquin, M ^a   Tauler, A ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Dexamethasone; Hepatic carbohydrate metabolism; Signal transduction

Indexed keywords

6 PHOSPHOFRUCTO 2 KINASE; DEXAMETHASONE; FRUCTOSE 2,6 BISPHOSPHATASE; GLUCOCORTICOID; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CATALYSIS; CELL SPECIFICITY; GENE EXPRESSION REGULATION; GENETIC REGULATION; GLUCONEOGENESIS; GLYCOLYSIS; IMMEDIATE EARLY GENE; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CHROMONES; DEXAMETHASONE; ENZYME INHIBITORS; FLAVONOIDS; FRUCTOSE-BISPHOSPHATASE; GENE EXPRESSION REGULATION; INSULIN; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; MULTIENZYME COMPLEXES; PHOSPHOFRUCTOKINASE-1; PHOSPHOFRUCTOKINASE-2; PLASMIDS; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SIROLIMUS; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0035862990     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3530267     Document Type: Article

References (47)

1. 6-Phosphofruoto-2-kinase/fructose-2,6-bisphosphatase: A metabolic signaling enzyme
2. Induction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA by refeeding and insulin
3. Expression of the liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA in FAO-1 cells
4. Insulin inhibits glucocorticoid-induced stimulation of liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene transcription
5. cAMP-independent synergistic effects of insulin and dexamethasone on fructose 2,6-bisphosphate metabolism in H411E cells
6. Inhibition of transcription of the phosphoenolpyruvate carboxykinase gene by insulin
7. Regulation of the phosphoenolpyruvate carboxykinase gene transcription by insulin and cAMP: Reciprocal actions on initiation and elongation
8. Insulin signal transduction through protein kinase cascades
9. Mitogen-activated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin
10. Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
11. Regulation of insulin-stimulated glucose transporter GLUT 4 translocation and Akt kinase activity by ceramide
12. Regulation of system A amino acid transport in 3T3-L1 adipocytes by insulin
13. The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: Evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf
14. Inhibition of glycogen synthase kinase-3 by insulin mediated by PKB
15. Activation of the ras mitogen-activated protein kinase ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gone transcription by insulin
16. Phosphatidylinositol 3-kinase, but not p70/p85 ribosomal S6 protein kinase, is required for the regulation of phosphoenolpyruvate carboxykinase gene expression by insulin. Dissociation of signaling pathways for insulin and phorbol ester regulation of phosphoenolpyruvate carboxykinase gene expression
17. Central role for phosphatidylinositide 3-kinase in the repression of glucose-6-phosphatase gene transcription by insulin
18. Wortmannin influences insulin regulation of gene 33 expression in rat hepatoma cells
19. Insulin regulation of glucose 6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase
20. Analysis of the signaling pathway involved in the regulation of hexokinase II gene transcription by insulin
21. Inhibition by insulin of glucose-induced gene transcription: Involvement of the ligand-binding domain of the glucocorticoid receptor and independence from the phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways
22. Regulation of gene expression of rat skeletal muscle/liver 6-phospholructo-2-kinase. Isolation and characterization of a glucocorticoid response element in the first intron of the gene
23. A cytoplasmic inhibitor of the c-Jun N-terminal kinase signal transduction pathway
24. ATF-2 contains a phosphorylation-dependent transcriptional activation domain
25. Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase
26. Isolation and characterization of the gene coding for cytosolic phosphoenolpyruvate carboxykinase (GTP) from the rat
27. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA
28. Expression of the bisphosphatase domain of rat liver 6-PF2K in Escherichia coli
29. Cloning and characterization of ribosomal RNA genes from wheat and barley
30. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells
31. Potential convergence of insulin and cAMP signal transduction systems of the phosphoenolpyruvate carboxykinase gene promoter through CCAAT/enhancer binding protein (C/EBP)
32. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY 294002)
33. Assessment of the roles of mitogen-activated protein kinase, phosphatidylinositol 3-kinase, PKB, and PKC in insulin inhibition of cAMP-induced phosphoenolpyruvate carboxykinase gene transcription
34. Phosphorylation and inhibition of rat glucocorticoid receptor transcriptional activation by glycogen synthase kinase-3 (GSK-3). Species-specific differences between human and rat glucocorticoid receptor signaling as revealed through GSK-3 phosphorylation
35. The immunosuppressant rapamycin induces inactivation of p7O SCK through dephosphorylation of a novel set of sites
36. Rapamycin selectively represses translation of the 'polypyrimidine tract' mRNA family
37. Requirement of MAP kinase for differentiation of fibroblasts to adipocytes for insulin activation of p90 S6 kinase and for insulin or serum stimulation of DNA synthesis
38. Dissociation between activation of Raf-1 kinase and the 42-kDa mitogen activated protein kinase/90-kDa S6 kinase (MAPK/RSK) cascade in the insulin/Ras pathway of adipocytic differentiation of 3T3 L1 cells
39. Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo
40. Insulin differentially regulates SAPKs/JNKs and ERKs in CHO cells overexpressing human insulin receptors
41. Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase
42. A synthetic inhibitor of the mitogen-activated protein kinase cascade
43. Mitogen-activated and cyclin-dependent protein kinases selectively and differentially modulate transcriptional enhancement
44. Hyperosmotic induction of the mitogen-activated protein kinase phosphatase MKP-1 in H411E rat hepatoma cells
45. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
46. MEKK-1 binds directly to the c-Jun N-terminal kinase/stress-activated protein kinases