Structural and functional abnormalities of the hippocampal formation in rats with environmentally induced reductions in prepulse inhibition of acoustic startle

Neuroscience

Volumn 103, Issue 2, 2001, Pages 315-323

  Greene, J R T ^a   Kerkhoff, J E ^a   Guiver, L ^a   Totterdell, S ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Electrophysiology; Interneurons; PPI; Schizophrenia; Subiculum

Indexed keywords

ANTIBODY; CALRETININ; ISOPROTEIN; NITRIC OXIDE SYNTHASE; PARVALBUMIN;

ACTION POTENTIAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENDRITE; DENTATE GYRUS; ELECTROPHYSIOLOGY; HIPPOCAMPUS; MALE; MEMBRANE STEADY POTENTIAL; MORPHOLOGY; NONHUMAN; PREPULSE INHIBITION; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SCHIZOPHRENIA; SOCIAL ISOLATION; STARTLE REFLEX; SUBICULUM;

ACOUSTIC STIMULATION; ACTION POTENTIALS; ANIMALS; BEHAVIOR, ANIMAL; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; ELECTROPHYSIOLOGY; HIPPOCAMPUS; INTERNEURONS; MALE; NEURAL INHIBITION; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE I; PARVALBUMINS; RATS; RATS, WISTAR; SCHIZOPHRENIA; SOCIAL ENVIRONMENT; SOCIAL ISOLATION; STARTLE REACTION;

EID: 0035857745     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00560-1     Document Type: Article

References (66)

1. Effects of the PCP analog dizocipine on sensory gating: Potential relevance to clinical subtypes of schizophrenia
2. Emerging principles of intrinsic hippocampal organization
3. Calretinin is present in non-pyramidal cells of the rat hippocampus III. Their inputs from the median raphe and medial septal nuclei
4. Neurons in the ventral subiculum, amygdala and entorhinal cortex which project to the nucleus accumbens - Their input from somatostatin-immunoreactive boutons
5. Antipsychotic drug action after lesions to the hippocampus or frontal cortex
6. Stimulation of the ventral subiculum of the hippocampus evokes glutamate receptor-mediated changes in dopamine efflux in the rat nucleus accumbens
7. Sensorimotor gating and schizophrenia. Human and animal model studies
8. Gating and habituation of startle reflex in schizophrenic patients
9. Carbachol infusion into the dentate gyrus disrupts sensorimotor gating of startle in the rat
10. Hippocampal modulation of acoustic startle and prepulse inhibition in the rat
11. + influx in rat cortical cultures
12. Potentiation of prepulse inhibition of the startle reflex in rats: Pharmacological evaluation of the procedure as a model for detecting antipsychotic activity
13. Prepulse inhibition of the startle reflex in rats: Effects of compounds acting at various sites on the NMDA receptor complex
14. The disruption of prepulse inhibition by social isolation in the Wistar rat: How robust is the effect?
15. Cysteamine blocks amphetamine-induced deficits in sensorimotor gating
16. The modulation of sensorimotor gating deficits by mesolimbic cholecystokinin
17. GABAergic septal and serotonergic median raphe afferents preferentially innervate inhibitory interneurons in the hippocampus and dentate gyrus
18. Interneurons in the hippocampus
19. Different reaction patterns in individually and socially reared rats during exposures to novel environments
20. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia
21. Intracerebral administration of metabotropic glutamate receptor antagonists disrupts prepulse inhibition of acoustic startle in Sprague-Dawley rats
22. The neuropsychology of schizophrenia
23. The subiculum: A potential site of action of novel antipsychotic drugs
24. Functional abnormalities in subicular neurons from rats with isolation-induced reductions in prepulse inhibition of acoustic startle
25. Differential expression of NADPH-diaphorase between electrophysiologically defined classes of pyramidal neurons in rat ventral subiculum, in vitro
26. Neuronal diversity in the subiculum: Correlations with the effects of somatostatin on intrinsic properties and on GABA mediated IPSPs, in vitro
27. Effects of somatostatin and related peptides on membrane potential and input resistance in rat ventral subicular neurons, in vitro
28. Morphology and distribution of electrophysiologically defined classes of pyramidal and non-pyramidal neurons in rat ventral subiculum, in vitro
29. Interneurons containing calretinin are specialized to control other interneurons in the rat hippocampus
30. The efficiency of systematic sampling in stereology and its prediction
31. On the neuropathology of schizophrenia and its dementia: Neurodevelopmental neurodegenerative, or both?
32. The neuropathology of schizophrenia
33. Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input
34. Schizophrenia: Problems in clinical practice
35. Dopaminergic and serotonergic function following isolation rearing in rats: Study of behavioural responses and postmortem and in vivo neurochemistry
36. The neurobiology of startle
37. Epidermal growth factor and fibroblast growth factor-2 have different effects on neuronal progenitors in the adult rat brain
38. Long-term effects of early social isolation in Macaca mulatta: Changes in dopamine receptor function following apomorphine challenge
39. Neonatal excitotoxic hippocampal damage in rats causes post-pubertal changes in prepulse inhibition of startle and its disruption by apomorphine
40. Dopaminergic stimulation disrupts sensorimotor gating in the rat
41. Social deprivation of infant rhesus monkeys alters the chemoarchitecture of the brain: I. Subcortical regions
42. Electrophysiology and burst-firing of rat subicular pyramidal neurons in vitro - A comparison with area CA1
43. Post-natal development of electrophysiological properties of rat cerebral cortical pyramidal neurons
44. The pattern of synaptophysin changes during maturation of the amygdaloid body and hippocampal hilus in the rat
45. Late maturation of GABA(B) synaptic transmission in area CA1 of the rat hippocampus
46. DNA fragmentation follows delayed neuronal death in CA1 neurons exposed to transient global ischaemia in the rat
47. The effects of hippocampal and fimbria-fornix lesions on prepulse inhibition
48. Proportion of parvalbumin-positive basket cells in the GABAergic innervation of pyramidal and granule cells of the rat hippocampal formation
49. Hyperactivity and obesity: The interaction of social isolation and cafeteria feeding
50. The effects of isolation rearing on exploration in the rats
51. Adrenergic alpha 2C receptors modulate the acoustic startle reflex, prepulse inhibition and aggression in mice
52. Multiple serotonin receptor sub-types modulate prepulse inhibition of the startle response in rats
53. Intrinsic properties and evoked responses of guinea pig subicular neurons in vitro
54. Effects of spiperone, raclopride, SCH 23390 and clozapine on apomorphine inhibition of sensorimotor gating of the startle response in the rat
55. Assessing the validity of an animal model of deficient sensorimotor gating in schizophrenic patients
56. Postnatal development of dopamine D4-like receptors in rat forebrain regions: Comparison with D2-like receptors
57. Electrophysiological properties of neurons in the rat subiculum in vitro
58. NADPH-diaphorase reactive pyramidal neurons in Ammon's horn and the subiculum of the rat hippocampal formation
59. Neonatal non-handling and in utero prenatal stress reduce the density of NADPH-diaphorase reactive neurons in the fascia denta and Ammon's horn of rats
60. Comparisons of the densities of NADPHd reactive and nNOS immunopositive neurons in the hippocampus of three age groups of young handled and nonhandled rats
61. Sensorimotor gating in rats is regulated by different dopamine-glutamate interactions in the nucleus accumbens core and shell subregions
62. Schizophrenia: From neuropathology to neurodevelopment
63. Evidence for dysfunction of the prefrontal-limbic network in schizophrenia: An MRI and rCBF study of discordant monozygotic twins
64. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response but does not disrupt latent inhibition
65. Disruption of prepulse inhibition following N-methyl-D-aspartate infusion into the ventral hippocampus is antagonized by clozapine but not by haloperidol: A possible model for the screening of atypical antipsychotics