WT1 regulates the expression of the major glomerular podocyte membrane protein Podocalyxin

Current Biology

Volumn 11, Issue 22, 2001, Pages 1805-1809

  Palmer, Rachel E ^a   Kotsianti, Angeliki ^b   Cadman, Brian ^a   Boyd, Theonia ^c   Gerald, William ^b   Haber, Daniel A ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c BAYSTATE MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE; CELL PROLIFERATION; DENYS DRASH SYNDROME; GENE EXPRESSION REGULATION; GENE TARGETING; GERM LINE; KIDNEY CELL; MEMBRANE PROTEIN; NEPHROBLASTOMA; PHENOTYPE; PODOCALYXIN; PODOCYTE; PROTEIN BINDING; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR GENE;

EID: 0035856480     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00560-7     Document Type: Article

References (22)

1. WT-1 is required for early kidney development
2. Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome
3. The nephropathy associated with male pseudohermaphroditism and Wilms' tumor (Drash syndrome): A distinctive glomerular lesion-report of 10 cases
4. Wilms tumor and the WT1 gene
5. Phenotypic conversions in renal development
6. Alternative splicing and genomic structure of the Wilms tumor gene WT1
7. Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing
8. The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin
9. The Wilms tumor suppressor gene WT1 is negatively autoregulated
10. The candidate Wilms' tumour gene is involved in genitourinary development
11. Identification and characterization of podocalyxin-the major sialoprotein of the renal glomerular epithelial cell
12. Molecular cloning and characterization of human podocalyxin-like protein
13. Sequence and structural requirements for high-affinity DNA binding by the WT1 gene product
14. Binding of the Wilms' tumor locus zinc finger protein to the EGR-1 consensus sequence
15. Biogenesis of podocalyxin-the major glomerular sialoglycoprotein-in the newborn rat kidney
16. Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin
17. Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aortagonad-mesonephros region
18. The Wilms tumor suppressor WT1 directs stage-specific quiescence and differentiation of human hematopoietic progenitor cells
19. Dysfunctions of cell biological mechanisms of visceral epithelial cell (podocytes) in glomerular diseases
20. Expression of podocalyxin inhibits cell-cell adhesion and modifies junctional properties in Madin-Darby canine kidney cells
21. Donor splice-site mutations in WT1 are responsible for Frasier syndrome
22. Two splice variants of the Wilms tumor 1 gene have distinct functions during sex determination and nephron formation