Identification of Human Macrophage Inflammatory Proteins 1α and 1β as a Native Secreted Heterodimer

Journal of Biological Chemistry

Volumn 276, Issue 15, 2001, Pages 12404-12409

  Guan, Ennan ^a   Wang, Jinhai ^b   Norcross, Michael A ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; BLOOD; CELL CULTURE; CELLS; DIMERS; MASS SPECTROMETRY; MONOMERS;

IMMUNOPRECIPITATION; INTERCELLULAR SIGNALING;

BIOCHEMISTRY;

ANTIBODY; CHEMOATTRACTANT; CHEMOKINE; CHEMOKINE RECEPTOR CCR5; HETERODIMER; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; UNCLASSIFIED DRUG; MACROPHAGE INFLAMMATORY PROTEIN 1; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL ACTIVATION; CELL CULTURE; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSOCIATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MASS SPECTROMETRY; PH MEASUREMENT; PRECIPITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; RECEPTOR INTRINSIC ACTIVITY; SIGNAL TRANSDUCTION; DIMERIZATION; METABOLISM;

CELLS, CULTURED; DIMERIZATION; GOLGI APPARATUS; HUMANS; MACROPHAGE INFLAMMATORY PROTEIN-1; RECOMBINANT PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0035853696     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M006327200     Document Type: Article

References (33)

1. Baggiolini, M., Dewald, B., and Moser, B. (1997) Annu. Rev. Immunol. 15, 675-705
2. Ward, S. G., and Westwick, J. (1998) Biochem. J. 333, 457-470
3. Cocchi, F., DeVico, A. L., Garzino-Demo, A., Arya, S. K., Gallo, R. C., and Lusso, P. (1995) Science 270, 1811-1815
4. Verani, A., Scarlatti, G., Comar, M., Tresoldi, E., Polo, S., Giacca, M., Lusso, P., Siccardi, A. G., and Vercelli, D. (1997) J. Exp. Med. 185, 805-816
5. Garzino-Demo, A., Moss, R. B., Margolick, J. B., Cleghorn, F., Sill, A., Blattner, W. A., Cocchi, F., Carlo, D. J., DeVico, A. L., and Gallo R. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 11986-11991
6. Skelton, N. J., Aspiras, F., Ogez, J., and Schall, T. J. (1995) Biochemistry 34, 5329-5342
7. Kim, K. S., Rajarathnam, K., Clark-Lewis, I., and Sykes, B. D. (1996) FEBS Lett. 395, 277-282
8. Chung, C. W., Cooke, R. M., Proudfoot, A. E., and Wells, T. N. (1995) Biochemistry 34, 9307-9314
9. Lodi, P. J., Garrett, D. S., Kuszewski, J., Tsang, M. L., Weatherbee, J. A., Leonard, W. J., Gronenborn, A. M., and Clore, G. M. (1994) Science 263, 1762-1767
10. Shao, W., Jerva, L. F., West, J., Lolis, E., and Schweitzer, B. I. (1998) Biochemistry 37, 8303-8313
11. Laurence, J. S., LiWang, A. C., and LiWang, P. J. (1998) Biochemistry 37, 9346-9354
12. Covell, D. G., Smythers, G. W., Gronenborn, A. M., and Clore, G. M. (1994) Protein Sci. 3, 2064-2072
13. Wang, J., Guan, E., Roderiquez, G., and Norcross, M. A. (1999) J. Immunol. 163, 5763-5769
14. Wang, J., Roderiquez, G., Oravecz, T., and Norcross, M. A. (1998) J. Virol. 72, 7642-7647
15. Tartakoff, A. M. (1983) Cell 32, 1026-1028
16. Korimilli, A., Gonzales, L. W., and Guttentag, S. H. (2000) J. Biol. Chem. 275, 8672-8679
17. Paolini, J. F., Willard, D., Consler, T., Luther, M., and Krangel, M. S. (1994) J. Immunol. 153, 2704-2717
18. Mayo, K. H., and Chen, M. J. (1989) Biochemistry 28, 9469-9478
19. Chen, M. J., and Mayo, K. H. (1991) Biochemistry 30, 6402-6411
20. Clark-Lewis, I., Kim, K. S., Rajarathnam, K., Gong, J. H., Dewald, B., Moser, B., Baggiolini, M., and Sykes, B. D. (1995) J. Leukocyte Biol. 57, 703-711
21. Clore, G. M., and Gronenborn, A. M. (1995) FASEB J. 9, 57-62
22. Sherry, B., Tekamp-Olson, P., Gallegos, C., Bauer, D., Davatelis, G., Wolpe, S. D., Masiarz, F., Coit, D., and Cerami, A. (1988) J. Exp. Med. 168, 2251-2259
23. Horcher, M., Rot, A., Aschauer, H., and Besemer, J. (1998) Cytokine 10, 1-12
24. St. Charles, R., Walz, D. A., and Edwards, B. F. (1989) J. Biol. Chem. 264, 2092-2099
25. Handel, T. M., and Domaille, P. J. (1996) Biochemistry 35, 6569-6584
26. Baldwin, E. T., Weber, I. T., St. Charles, R., Xuan, J. C., Appella, E., Yamada, M., Matsushima, K., Edwards, B. F., Clore, G. M., and Gronenborn, A. M. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 502-506
27. Fairbrother, W. J., Reilly, D., Colby, T., and Horuk, R. (1993) FEBS Lett. 330, 302-306
28. Kim, K. S., Clark-Lewis, I., and Sykes, B. D. (1994) J. Biol. Chem. 269, 32909-32915
29. Malkowski, M. G., Wu, J. Y., Lazar, J. B., Johnson, P. H., and Edwards, B. F. (1995) J. Biol. Chem. 270, 7077-7087
30. Zhang, X., Chen, L., Bancroft, D. P., Lai, C. K., and Maione, T. E. (1994) Biochemistry 33, 8361-8366
31. Zhang, Y., and Rollins, B. J. (1995) Mol. Cell. Biol. 15, 4851-4855
32. Rajarathnam, K., Sykes, B. D., Kay, C. M., Dewald, B., Geiser, T., Baggiolini, M., and Clark-Lewis, I. (1994) Science 264, 90-92
33. Laurence, J. S., Blanpain, C., Burgner, J. W., Parmentier, M., and LiWang, P. J. (2000) Biochemistry 39, 3401-3409