Modeling of the drug delivery from a hydrophilic transdermal therapeutic system across polymer membrane

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 49, Issue 3, 2000, Pages 287-293

  Iordanskii, Alexei L ^a   Feldstein, Mikhail M ^b   Markin, Valery S ^a   Hadgraft, Jonathan ^c   Plate, Nicolai A ^a  

^a SEMENOV INSTITUTE OF CHEMICAL PHYSICS   (Russian Federation)

^b TOPCHIEV INSTITUTE OF PETROCHEMICAL SYNTHESIS   (Russian Federation)

^c CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Adhesive hydrogel matrix; Drug diffusion; Partition; Poly(dimethyl siloxane) polycarbonate block copolymer; Poly(ethylene glycol); Poly(vinyl pyrrolidone); Propranolol; Skin mimetic membrane; Transdermal drug delivery, Mathematical simulation

Indexed keywords

CARBOSIL; MACROGOL; POLYMER; POVIDONE; PROPRANOLOL; UNCLASSIFIED DRUG;

ARTICLE; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; HYDRATION; IN VITRO STUDY; KINETICS; MATHEMATICAL MODEL; MEMBRANE PERMEABILITY; THEORY; TRANSDERMAL DRUG ADMINISTRATION;

EID: 0034595313     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(00)00063-1     Document Type: Article

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