Arkadia enhances nodal-related signalling to induce mesendoderm

Nature

Volumn 410, Issue 6830, 2001, Pages 830-834

  Niederländer, Christiane ^a   Walsh, James J ^b   Episkopou, Vasso ^b   Jones, C Michael ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b HAMMERSMITH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GENES; MUTAGENESIS; PROTEINS; TISSUE;

GENE EXPRESSIONS;

GENETIC ENGINEERING;

MUTANT PROTEIN; NUCLEAR PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; ENDODERM; GENE EXPRESSION; GENE EXPRESSION REGULATION; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; XENOPUS;

ANIMALS; BODY PATTERNING; BONE MORPHOGENETIC PROTEINS; EMBRYONIC INDUCTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GOOSECOID PROTEIN; HOMEODOMAIN PROTEINS; MESODERM; MICE; NUCLEAR PROTEINS; ORGANIZERS, EMBRYONIC; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; T-BOX DOMAIN PROTEINS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; XENOPUS; XENOPUS PROTEINS;

EID: 0035848854     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35071103     Document Type: Article

References (29)

1. Nodal signalling in vertebrate development
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3. A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse
4. Zebrafish organizer development and germ-layer formation require nodal-related signals
5. cyclops encodes a nodal-related factor involved in midline signaling
6. Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling
7. Nodal is a novel TGF-β-like gene expressed in the mouse node during gastrulation
8. The head inducer Cerberus is a multifunctional antagonist of Nodal, BMP and Wnt signals
9. The EGF-CFC protein one-eyed pinhead is essential for nodal signaling
10. Regulation of midline development by antagonism of lefty and nodal signaling
11. Induction of the mammalian node requires Arkadia function in the extra-embryonic lineages
12. Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo
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15. The Spemann organizer signal noggin binds and inactivates Bone Morphogenetic Protein 4
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