Potent synthetic inhibitors of tyrosyl tRNA synthetase derived from C-pyranosyl analogues of SB-219383

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 5, 2001, Pages 715-718

  Jarvest, Richard L ^a   Berge, John M ^a   Brown, Pamela ^a   Hamprecht, Dieter W ^a   McNair, David J ^a   Mensah, Lucy ^a   O'Hanlon, Peter J ^a   Pope, Andrew J ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ARABINOSE; BACTERIAL ENZYME; ENZYME INHIBITOR; TYROSINE TRANSFER RNA LIGASE; TYROSYL 2 AMINO 2 (2,4,5,8 TETRAHYDROXY 7 OXA 2 AZABICYCLO[3.2.1]OCT 3 YL)ACETIC ACID; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; STAPHYLOCOCCUS AUREUS; STEREOCHEMISTRY;

BACTERIAL PROTEINS; BICYCLO COMPOUNDS, HETEROCYCLIC; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FURANS; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PYRANS; STAPHYLOCOCCUS AUREUS; TYROSINE-TRNA LIGASE;

BACTERIA (MICROORGANISMS);

EID: 0035848397     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00040-3     Document Type: Article

References (10)