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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 3, 2001, Pages 429-431

Cytotoxic Michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone

(5) Lawrence, Nicholas J a,c McGown, Alan T b Nduka, Jane a,b Hadfield, John A b Pritchard, Robin G a

a UNIVERSITY OF MANCHESTER (United Kingdom)

b CHRISTIE HOSPITAL (United Kingdom)

c CARDIFF UNIVERSITY (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANTOLACTONE; ISOALANTOLACTONE; LACTONE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN K 562; CELL STRAIN MCF 7; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG EFFICACY; DRUG SYNTHESIS; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; REACTION ANALYSIS; STEREOCHEMISTRY; TUMOR GROWTH;

AMINES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL DIVISION; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; LACTONES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0035847680 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00686-7 Document Type: Article

Times cited : (85)

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