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Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 3, 2001, Pages 309-312

Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase

(7) Corbett, Jeffrey W a,b Kresge, Kristen J a Pan, Senliang a Cordova, Beverly C a Klabe, Ronald M a Rodgers, James D a Erickson Viitanen, Susan K a

a DUPONT COMPANY (United States)

b Pharmacia 7255 209 643 ^* (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 [(4,7 DICHLORO 2 BENZOXAZOLYLMETHYL)AMINO] 5 ETHYL 6 METHYL 2(1H) PYRIDONE; 6 CHLORO 4 (2 CYCLOPROPYLVINYL) 3,4 DIHYDRO 4 TRIFLUOROMETHYL 2(1H) QUINAZOLINONE; 6 CHLORO 4 CYCLOPROPYLETHYNYL 3,4 DIHYDRO 4 TRIFLUOROMETHYL 2(1H) QUINAZOLINONE; EFAVIRENZ; PYRIDONE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; VIRUS INHIBITION;

ANTI-HIV AGENTS; COMBINATORIAL CHEMISTRY TECHNIQUES; CYTOPATHOGENIC EFFECT, VIRAL; ENZYME INHIBITORS; FLUORINE; HIV-1; HIV-1 REVERSE TRANSCRIPTASE; INHIBITORY CONCENTRATION 50; MUTATION; PYRIDONES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035847679 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/S0960-894X(00)00662-4 Document Type: Article

Times cited : (21)

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