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Volumn 44, Issue 21, 2001, Pages 3402-3406

Synthesis of potent C2-symmetric, diol-based HIV-1 protease inhibitors. Investigation of thioalkyl and thioaryl P1/P1′ substituents

(4) Muhlman A a Classon, B a,b Hallberg, A c Samuelsson, B a,b

a STOCKHOLM UNIVERSITY (Sweden)

b MEDIVIR AB (Sweden)

c UPPSALA UNIVERSITY (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; ANTIRETROVIRUS AGENT; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROTEINASE INHIBITOR; THIOL GROUP;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; STRUCTURE ACTIVITY RELATION;

CELL LINE; CLONING, MOLECULAR; CYTOPATHOGENIC EFFECT, VIRAL; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE-ACTIVITY RELATIONSHIP; THIOPHENES;

EID: 0035846163 PISSN: 00222623 EISSN: None Source Type: Journal
DOI: 10.1021/jm0011169 Document Type: Article

Times cited : (19)

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