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Agenerase Package Insert
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Phase I clinical trial with a novel protease inhibitor for HIV, KVX-478 in healthy male volunteers
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Cytochrome p-450 isoenzyme induction, inhibition and metabolism studies with the HIV protease inhibitor, 141W94
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Sept 28-Oct 1, Toronto. Abstract A-60
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Woolley J, Studenberg S, Boehlert C, et al. Cytochrome p-450 isoenzyme induction, inhibition and metabolism studies with the HIV protease inhibitor, 141W94. Presented at: 37th Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); Sept 28-Oct 1, 1997; Toronto. Abstract A-60.
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Lederman, M.2
Haas, D.3
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17
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Combination Ziagen (abacavir, ABC)/Amprenavir (141,APV-USAN) therapy in HIV-1 infected antiretroviral naive subjects with CD4+ counts > 400 copies/μl
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Jan 31-Feb 4, Chicago. Abstract 626
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Bart PA, Rizzardi GP, Gallant S, et al. Combination Ziagen (abacavir, ABC)/Amprenavir (141,APV-USAN) therapy in HIV-1 infected antiretroviral naive subjects with CD4+ counts > 400 copies/μl. Presented at: Sixth Conference on Retroviruses and Opportunistic Infections; Jan 31-Feb 4, 1999; Chicago. Abstract 626.
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Sixth Conference on Retroviruses and Opportunistic Infections
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Bart, P.A.1
Rizzardi, G.P.2
Gallant, S.3
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18
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0344315254
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Potent, durable combination therapy with abacavir, amprenavir, and AZT/3TC in subjects acutely and chronically infected with HIV-1
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Jan 31-Feb 4, Chicago. Abstract 639
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Kost R, Cao Y, Zhang L, et al. Potent, durable combination therapy with abacavir, amprenavir, and AZT/3TC in subjects acutely and chronically infected with HIV-1. Presented at: Sixth Conference on Retroviruses and Opportunistic Infections; Jan 31-Feb 4, 1999; Chicago. Abstract 639.
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Sixth Conference on Retroviruses and Opportunistic Infections
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Pediatric trial of combination therapy including the protease inhibitor amprenavir
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Jan 31-Feb 4, Chicago. Abstract 430
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Sixth Conference on Retroviruses and Opportunistic Infections
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Yogev, R.1
Church, J.2
Flynn, P.3
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21
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Salvage therapy with abacavir, amprenavir, and efavirenz in subjects with plasma HIV-1 RNA > 500 copies/ml despite protease inhibitor therapy
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Nov 12-15, Denver. Poster 441
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Falloon J, Masur H, Brosgart C, et al. Salvage therapy with abacavir, amprenavir, and efavirenz in subjects with plasma HIV-1 RNA > 500 copies/ml despite protease inhibitor therapy. Presented at: Infectious Diseases Society of America 36th Annual Meeting; Nov 12-15, 1998; Denver. Poster 441.
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Infectious Diseases Society of America 36th Annual Meeting
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Falloon, J.1
Masur, H.2
Brosgart, C.3
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22
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0344315253
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Amprenavir (141W94, APV USAN approved)/ 3TC/AZT is superior to 3TC/AZT in HIV-1 infected antiretroviral therapy-naive subjects
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Sept 24-27, San Diego. Abstract LB-5
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Goodgame J, Stein A, Pottage J, et al. Amprenavir (141W94, APV USAN approved)/ 3TC/AZT is superior to 3TC/AZT in HIV-1 infected antiretroviral therapy-naive subjects. Presented at: 38th Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); Sept 24-27, 1998; San Diego. Abstract LB-5.
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38th Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
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Goodgame, J.1
Stein, A.2
Pottage, J.3
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23
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0005980458
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141W94 with or without zidovudine/3TC in patients with no prior protease inhibitor or 3TC therapy-ACTG 347
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Feb 1-5, Chicago. Abstract 512
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Murphy R, Degruttola V, Gulick R, et al. 141W94 with or without zidovudine/3TC in patients with no prior protease inhibitor or 3TC therapy-ACTG 347. Presented at: Fifth Conference on Retroviruses and Opportunistic Infections; Feb 1-5, 1998; Chicago. Abstract 512.
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Fifth Conference on Retroviruses and Opportunistic Infections
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Murphy, R.1
Degruttola, V.2
Gulick, R.3
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24
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0009554752
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Amprenavir (141W94, APV USAN approved): Review of overall safety profile
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Jan 31-Feb 4, Chicago. Abstract 386
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Pedneault L, Fetter A, Hanson C, et al. Amprenavir (141W94, APV USAN approved): Review of overall safety profile. Presented at: Sixth Conference on Retroviruses and Opportunistic Infections; Jan 31-Feb 4, 1999; Chicago. Abstract 386.
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Sixth Conference on Retroviruses and Opportunistic Infections
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Pedneault, L.1
Fetter, A.2
Hanson, C.3
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25
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0006532917
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An overview of the preclinical development of the HIV protease inhibitor VX-478 (141W94)
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Jan 29-Feb 2, Washington, DC. Abstract LB5
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Painter GR, St.Clair MH, Demiranda P, et al. An overview of the preclinical development of the HIV protease inhibitor VX-478 (141W94). Presented at: Second National Conference on Human Retroviruses; Jan 29-Feb 2, 1995; Washington, DC. Abstract LB5.
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Second National Conference on Human Retroviruses
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Painter, G.R.1
St.Clair, M.H.2
Demiranda, P.3
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30
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Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir
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Kempf, D.J.1
Marsh, K.C.2
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31
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0013472220
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Pharmacokinetic interaction between ketoconazole and the HIV protease inhibitor 141W94 after single dose administration to normal volunteers
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Sept 28-Oct 1, Toronto. Abstract A-61
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Polk RE, Israel DS, Pastor A, et al. Pharmacokinetic interaction between ketoconazole and the HIV protease inhibitor 141W94 after single dose administration to normal volunteers. Presented at: 37th Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); Sept 28-Oct 1, 1997; Toronto. Abstract A-61.
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37th Annual Meeting of the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
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Polk, R.E.1
Israel, D.S.2
Pastor, A.3
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32
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1999 Drug Topics Red Book. Montvale, NJ: Medical Economics Co.
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1999 Drug Topics Red Book
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