Long lasting antinociceptive properties of enkephalin degrading enzyme (NEP and APN) inhibitor prodrugs

Journal of Medicinal Chemistry

Volumn 44, Issue 21, 2001, Pages 3523-3530

  Chen, H ^a   Noble, F ^a   Roques, B P ^a   Fournie Zaluski M C ^a  

^a Laboratoire de Pharmacochimie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENKEPHALINASE INHIBITOR; MEMBRANE METALLOENDOPEPTIDASE; MICROSOMAL AMINOPEPTIDASE; PRODRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; BIOAVAILABILITY; BRAIN MEMBRANE; CONTROLLED STUDY; DRUG ACTIVATION; DRUG HYDROLYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; HOT PLATE TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; RAT; SERUM;

EID: 0035846127     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0102248     Document Type: Article

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