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0011460752
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note
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For discussion of another possible reason of hindered rotation of an aromatic ring see ref 2f.
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29
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0001632467
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note
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9 in THF solution at 40°C. The conditions are similar to those reported for isomerization of N,N-diallybenzamide (1a) to N-vinylbenzamide: Murai, T.; Kasai, Z.; Ishihara, H.; Kato, S. J. Org. Chem. 1992, 57, 5542. However, the isomerization leading to carbenes 6 and 7 is much faster even at -78°C.
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Hydrochloride of 1-amino-3-butene was prepared in 81% yield by Curtius reaction of 4-pentenoyl chloride with inactivated sodium azide and subsequent hydrolysis by 36% hydrochloric acid analogously as described in: Smith, P. A. S. Organic Reactions, III; J. Wiley: New York, 1946; p 387, for the preparation of benzylamine hydrochloride. Mp: 167-173°C.
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34
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0011419969
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note
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3).
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