Bacteriophage λ DNA packaging: DNA site requirements for termination and processivity

Journal of Molecular Biology

Volumn 311, Issue 2, 2001, Pages 233-240

  Cue, David ^a   Feiss, Michael ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

DNA translocation; Viral endonuclease; Virus assembly; Virus DNA packaging; Virus DNA processing

Indexed keywords

BACTERIOPHAGE DNA; ENDONUCLEASE; VIRUS DNA;

ARTICLE; BACTERIOPHAGE LAMBDA; BASE PAIRING; BINDING SITE; DNA PACKAGING; DNA SEQUENCE; DNA TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION INITIATION; VIRION; VIRUS ASSEMBLY;

BACTERIOPHAGE 21; BACTERIOPHAGE LAMBDA;

EID: 0035838978     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.4840     Document Type: Article

References (34)

1. DNA packaging in dsDNA bacteriophages
2. Structure, function, and specificity of the DNA packaging signals in double-stranded DNA viruses
3. The terminase enzyme from bacteriophage lambda: A DNA-packaging machine
4. Early events in the in vitro packaging of bacteriophage DNA
5. Assembly of a nucleoprotein complex required for DNA packaging by bacteriophage lambda
6. Specific interaction of terminase, the DNA packaging enzyme of bacteriophage lambda, with the portal protein of the prohead
7. Processive action of terminase during sequential packaging of bacteriophage lambda chromosomes
8. Bacteriophage lambda derivatives carrying two copies of the cohesive end site
9. Termination of packaging of the bacteriophage lambda chromosome: cosQ is required for nicking the bottom strand of cosN
10. Genetic analysis of cosB, the binding site for terminase, the DNA packaging enzyme of bacteriophage lambda
11. DNA sequences necessary for packaging of bacteriophage λ DNA
12. Headful packaging revisited: The packaging of more than one DNA molecule into a bacteriophage P1 head
13. A discontinuous headful packaging model for packaging less than headful length DNA molecules by bacteriophage T4
14. Structure of the bacteriophage lambda cohesive end site. Genetic analysis of the site (cosN) at which nicks are introduced by terminase
15. Separate sites for binding and nicking of bacteriophage lambda DNA by terminase
16. The role of cosB, the binding site for terminase, the DNA packaging enzyme of bacteriophage lambda, in the nicking reaction
17. Mutations abolishing the endonuclease activity of bacteriophage λ terminase lie in two distict regions of the A gene, one of which may encode a leucine zipper DNA binding domain
18. Mutations affecting the high affinity ATPase center of gpA, the large subunit of bacteriophage lambda terminase, inactivate the endonuclease activity of terminase
19. Mechanism of cos DNA cleavage by bacteriophage lambda terminase: Multiple roles of ATP
20. Chromosome end formation in phage lambda, catalyzed by terminase, is controlled by two DNA elements of cos, cosN and R3, and by ATP
21. HU and integration host factor function as auxiliary proteins in cleavage of phage lambda cohesive ends by terminase
22. The bacteriophage lambda cohesive end site: Isolation of spacing/substitution mutations that result in dependence on Escherichia coli integration host factor
23. Searching for and predicting the activity of sites for DNA binding proteins: Compilation and analysis of the binding sites for Escherichia coli integration host factor (IHF)
24. The lambda terminase enzyme measures the point of its endo-nucleolytic attack 47 ± 2 bp away from its site of specific DNA binding, the R site
25. Mutations in Nu1, the gene encoding the small subunit of bacteriophage λ terminase, suppress the postcleavage DNA packaging defect of cosB mutations
26. A site required for termination of packaging of the phage lambda chromosome
27. Genetic evidence that recognition of cosQ, the signal for termination of phage λ DNA packaging, depends on the extent of head filling
28. Bacteriophage lambda and 21 packaging specificities
29. Bacteriophage lambda DNA packaging: Scanning for the terminal cohesive end site during packaging
30. Bacteriophage lambda DNA: The beginning of the end
31. Defining cosQ, the site required for termination of bacteriophage λ DNA packaging
32. Completed annotated lambda sequence
33. Mutations in Nu1, the gene encoding the small subunit of bacteriophage lambda terminase, suppress the postcleavage DNA packaging defect of cosB mutations
34. Experimental methods for use with lambda