Defining cosQ the site required for termination of bacteriophage λ DNA packaging

Genetics

Volumn 158, Issue 2, 2001, Pages 495-506

  Wieczorek, D J ^a   Feiss, M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA; ENZYME; RESTRICTION ENDONUCLEASE;

ARTICLE; BACTERIOPHAGE LAMBDA; CHROMOSOME; DNA NICK TRANSLATION; DNA PACKAGING; DNA VIRUS; ESCHERICHIA COLI; GENE INSERTION; GENE SEQUENCE; GENE STRUCTURE; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL;

BACTERIOPHAGE LAMBDA; BASE SEQUENCE; DNA, VIRAL; GENOME, VIRAL; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PHENOTYPE; PLASMIDS; RECOMBINATION, GENETIC;

BACTERIOPHAGE LAMBDA; DNA VIRUSES; ESCHERICHIA COLI; UNIDENTIFIED BACTERIOPHAGE;

EID: 0034972541     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. Experimental methods for use with lambda
2. An accessory role for integration host factor: Characterization of a lambda mutant dependent upon integration host factor for DNA packaging
3. Bacteriophage λ DNA: The beginning of the end
4. Early events in the in vitro packaging of bacteriophage λ DNA
5. Virus DNA packaging: The strategy, used by phage λ
6. Genetic analysis of cosB, the binding site for terminase, the DNA packaging enzyme of bacteriophage λ
7. A site required for the termination of packaging of the phage λ chromosome
8. Genetic evidence that recognition of cosQ, the signal for termination of phage λ DNA packaging, depends on the extent of head filling
9. Termination of packaging of the bacteriophage λ chromosome: cosQ is required for nicking the bottom strand of cosN
10. Completed annotated lambda sequence
11. A novel in vitro DNA packaging system demonstrating a direct role for the bacteriophage λ FI gene product
12. Mutations abolishing the endonuclease activity of bacteriophage λ terminase lie in two distinct regions of the A gene, one of which may encode a "leucine zipper" DNA binding domain
13. Bacteriophage lambda derivatives carrying two copies of the cohesive end site
14. Terminase and the recognition, cutting, and packaging of λ chromosomes
15. DNA packaging and cutting
16. Structure of the bacteriophage lambda cohesive end site: Location of the sites of terminase binding (cosB) and nicking (cosN)
17. Processive action of terminase during sequential packaging of bacteriophage λ chromosomes
18. A functional domain of bacteriophage λ terminase for prohead binding
19. The role of gene 49 in DNA replication and head morphogenesis in bacteriophage T4
20. Lambda DNA replication
21. Association of Holliday-structure resolving endonuclease VII with gp20 from the packaging machine of T4
22. Studies on transformation of Escherichia coli with plasmids
23. The λ terminase enzyme measures the point of its endonucleolytic attack 47 ± 2 bp away from its site of specific DNA binding, the R site
24. Interaction of terminase, the DNA packaging enzyme of phage λ, with its cos DNA substrate
25. Mechanisms of cos DNA cleavage by bacteriophage λ terminase: Multiple roles of ATP
26. DNA sequences necessary for packaging of bacteriophage λ DNA
27. A defined system for in vitro λ DNA packaging
28. Mutations affecting the high affinity ATPase center of gpA, the large subunit of bacteriophage λ terminase, inactivate the endonuclease activity of terminase
29. On the nature of gene 49-defective heads and their role as intermediates
30. The bacteriophage λ cohesive end site: Isolation of spacing/substitution mutations that result in dependence on Escherichia coli integration host factor
31. Restriction endonuclease EcoO 109I from Escherichia coli H709c with heptanucleotide recognition site 5′-PuG↓GNCCPy
32. Lambda phage DNA sequences affecting the packaging process
33. T4 endonuclease VII cleaves Holliday structures
34. P1 plasmid replication: Initiator sequestration is inadequate to explain control by initiator-binding sites
35. Genomic sequence and analysis of the atypical temperate bacteriophage N15
36. The in vitro endonuclease activity of gene product A, the large subunit of the bacteriophage λ terminase, and its relationship to the endonuclease activity of the holoenzyme
37. The in vitro ATPases of bacteriophage λ terminase and its large subunit, gene product A
38. Nucleotide sequence of bacteriophage lambda DNA
39. The Nu1 subunit of bacteriophage lambda binds to specific sites in cos DNA
40. Analysis of a mutation affecting the specificity domain for prohead binding of the bacteriophage λ terminase
41. Mutations that extend the specificity of the endonuclease activity of λ terminase
42. Bacteriophage P4: A satellite virus depending on a helper such as prophage P2
43. Sites and gene products involved in lambdoid phage DNA packaging
44. Isolation and characterization of P1 minireplicons, 1-P1:5R and 1-P1:5L
45. Domains for protein-protein interactions at the N- and C-termini of the large subunit of bacteriophage λ terminase
46. Structure of the bacteriophage λ cohesive end site: Genetic analysis of the site (cosN) at which nicks are introduced by terminase
47. The last duplex base-pair of the phage λ chromosome: Involvement in packaging, ejection, and routing of λ DNA
48. Mutational analysis of the prohead binding domain of the large subunit of terminase, the bacteriophage λ DNA packaging enzyme
49. Specific interaction of terminase, the DNA packaging enzyme of bacteriophage λ, with the portal protein of the prohead
50. Structure of the bacteriophage λ cohesive end site: Bent DNA on both sides of the site, cosN, at which terminase introduces nicks during chromosome maturation