Increased DNA double strand breakage is responsible for sensitivity of the pso3-1 mutant of Saccharomyces cerevisiae to hydrogen peroxide

Mutation Research - DNA Repair

Volumn 485, Issue 4, 2001, Pages 345-355

  Brozmanova J ^a   Vlckova V ^a   Farkasova E ^a   Dudas A ^a   Vlasakova D ^a   Chovanec, M ^a   Mikulovska Z ^a   Fridrichova I ^a   Saffi, J ^a   Henriques, J A P ^a  

^a CANCER RESEARCH INSTITUTE   (Slovakia)

Author keywords

Base excision repair; DNA double strand breakage; E. coli endonuclease III; Hydrogen peroxide; Oxidative stress; Pso3 function

Indexed keywords

DOUBLE STRANDED DNA; ENDONUCLEASE; HYDROGEN PEROXIDE; MUTANT PROTEIN; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN NTG1; PROTEIN NTG2; PYRIMIDINE; UNCLASSIFIED DRUG;

ARTICLE; CELL MUTANT; DNA DAMAGE; DNA STRAND BREAKAGE; FUNGAL GENETICS; FUNGUS MUTANT; GENE EXPRESSION; GENETIC COMPLEMENTATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY;

BLEOMYCIN; DEOXYRIBONUCLEASE (PYRIMIDINE DIMER); DNA DAMAGE; ELECTROPHORESIS, GEL, PULSED-FIELD; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENES, FUNGAL; GENETIC COMPLEMENTATION TEST; HYDROGEN PEROXIDE; METHYL METHANESULFONATE; MUTAGENS; MUTATION; PARAQUAT; SACCHAROMYCES CEREVISIAE;

ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE;

EID: 0035837642     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(01)00070-2     Document Type: Article

References (40)

1. DNA damages processed by base excision repair: Biological consequences
2. Repair of oxidative damage to DNA: Enzymology and biology
3. The base excision repair pathway
4. Prokaryotic base excision repair
5. DNA N-glycosylases and UV repair
6. Properties and biological functions of the NTH and FPG proteins of Escherichia coli: Two DNA glycosylases that repair oxidative damage in DNA
7. Structure and function of Escherichia coli endonuclease III
8. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily
9. Repair of oxidized DNA bases in the yeast Saccharomyces cerevisiae
10. DNA glycosylases
11. Yeast redoxyendonuclease, a DNA repair enzyme similar to Echerichia coli endonuclease III
12. Purification, characterization, gene cloning, and expression of Saccharomyces cerevisiae redoxyendonuclease, a homolog of Escherichia coli endonuclease III
13. Saccharomyces cerevisiae possesses two functional homologues of Escherichia coli endonuclease III
14. Saccharomyces cerevisiae Ntg1p and Ntg2p: Broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria
15. The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast
16. Base excision of oxidative purine and pyrimidine DNA damage in Saccharomyces cerevisiae by a DNA glycosylase with sequence similarity to endonuclease III from Escherichia coli
17. Overlapping specificities of base excision repair, nucleotide excision repair, recombination, and translesion synthesis pathways for DNA base damage in Saccharomyces cerevisiae
18. The role of PSO and SNM genes in DNA repair of the yeast Saccharomyces cerevisiae
19. Role of PSO genes in the repair of photoinduced interstrand cross-links and photooxidative damage in the DNA of the yeast Saccharomyces cerevisiae
20. Low glutathione pools in the original pso3 mutant of Saccharomyces cerevisiae are responsible for its pleiotropic sensitivity phenotype
21. The DNA repair gene PSO3 of Saccharomyces cerevisiae belongs to the RAD3 epistasis group
22. The effects of three PSO genes on induced mutagenesis: A novel class of mutationally defective yeast
23. Mutagenesis induced by mono- and bi-functional alkylating agents in yeast mutants sensitive to photoaddition of furocoumarins (pso)
24. The E. coli RecA gene can restore the defect in mutagenesis of the pso4-1 mutant of S. cerevisiae
25. Isolation and characterization of pso mutants sensitive to photo-addition of psoralen derivatives in Saccharomyces cerevisiae
26. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
27. A family of yeast expression vectors containing the phage f1 intergenic region
28. cDNA cloning and functional expression in yeast Saccharomyces cerevisiae of beta-naphthoflavone-induced rabbit liver P-450 LM4 and LM6
29. DMSO-enhanced whole cell yeast transformation
30. The Escherichia coli recA gene increases resistance of the yeast Saccharomyces cerevisiae to ionizing and ultraviolet radiation
31. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
32. Molecular mechanism of potentially lethal damage repair. I. Enhanced fidelity of DNA double-strand break rejoining under conditions allowing potentially lethal damage repair
33. Genetic map of Saccharomyces cerevisiae (Edition 9)
34. Enzymatic processing of radiation-induced free radical damage in DNA
35. Reactive oxygen species-induced DNA damage and its modification: A chemical investigation
36. Yeast structural gene (APN1) for the major apurinic endonuclease: Homology to Escherichia coli endonuclease IV
37. Cloning a eukaryotic DNA glycosylase repair gene by the suppression of a DNA repair defect in Escherichia coli
38. Normal processing of AP sites in Apn1-deficient Saccharomyces cerevisiae is restored by Escherichia coli genes expressing either exonuclease III or endonuclease III
39. AP lyases and dRPases: Commonality of mechanism
40. Functional expression of Escherichia coli endonuclease IV in apurinic endonuclease-deficient yeast