The cloning, genomic organization and expression of the focal contact protein paxillin in Drosophila

Gene

Volumn 262, Issue 1-2, 2001, Pages 291-299

  Wheeler, Grant N ^a,b   Hynes, Richard O ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Drosophila; Embryogenesis; Focal adhesions; Mesoderm; Paxillin

Indexed keywords

COMPLEMENTARY DNA; FOCAL ADHESION KINASE; INTEGRIN; MESSENGER RNA; PAXILLIN; PROTEIN KINASE P60;

ANIMAL CELL; ARTICLE; CELL ADHESION; DROSOPHILA; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE SEQUENCE; MESODERM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; VERTEBRATE;

3T3 CELLS; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL ADHESION MOLECULES; CELL MOVEMENT; CELL SIZE; CLONING, MOLECULAR; CYTOSKELETAL PROTEINS; DROSOPHILA; DROSOPHILA PROTEINS; EMBRYO, NONMAMMALIAN; FOCAL ADHESION KINASE 1; FOCAL ADHESION PROTEIN-TYROSINE KINASES; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; PAXILLIN; PHOSPHOPROTEINS; PROTEIN-TYROSINE KINASES; REPETITIVE SEQUENCES, AMINO ACID;

VERTEBRATA;

EID: 0035834954     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(00)00512-6     Document Type: Article

References (30)

1. The genome sequence of Drosophila melanogaster
2. Vinculin gene is non-essential in Drosophila melanogaster
3. Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts
4. Paxillin LD motifs may define a new family of protein recognition domains
5. Identification of LIM3 as the principal determinant of paxillin focal adhesion localization and characterization of a novel motif on paxillin directing vinculin and focal adhesion kinase binding
6. Null mutations in the alpha PS2 and beta PS integrin subunit genes have distinct phenotypes
7. Expression of DFak56, a Drosophila homolog of vertebrate focal adhesion kinase, supports a role in cell migration in vivo
8. Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster
9. Novel tyrosine kinase substrates from Rous sarcoma virus-transformed cells are present in the membrane skeleton
10. Drosophila PS1 integrin is a laminin receptor and differs in ligand specificity from PS2
11. Constructing and screening cDNA libraries in lgt10 and lgt11
12. The evolution of cell adhesion
13. The function of PS integrins during Drosophila embryogenesis
14. Leupaxin is a novel LIM domain protein that forms a complex with PYK2
15. Paxillin isoforms in mouse. Lack of the gamma isoform and developmentally specific beta isoform expression
16. A whole-genome assembly of Drosophila
17. DFak56 is a novel Drosophila melanogaster focal adhesion kinase
18. Control of epithelial morphogenesis by cell signaling and integrin molecules in the Drosophila foregut
19. Comparative genomics of the eukaryotes
20. The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells
21. A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development
22. Characterization of a focal adhesion protein Hic-5, that shares extensive homology with paxillin
23. The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase
24. Paxillin is a major phosphotyrosine-containing protein during embryonic development
25. Paxillin
26. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat ARF-GAP protein: A role in cytoskeletal remodeling
27. Paxillin: A new vinculin-binding protein present in focal adhesions
28. Primary sequence of paxillin contains putative SH2 and SH3 domain binding motifs and multiple LIM domains: Identification of a vinculin and pp125Fak-binding region
29. Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules
30. The phenogenetics of the embryonic mutant, lethal myospheroid, in Drosophila melanogaster