Nuclear factor-κB decoy: Infiltrating the heart of the matter in inflammatory heart disease

Circulation Research

Volumn 89, Issue 10, 2001, Pages 850-852

  Liu, Peter P ^a   Le, Jenny ^a   Nian, Min ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

Inflammation; Molecular decoy; Myocarditis; Nuclear factor B; Transcription factor

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOSOME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERCELLULAR ADHESION MOLECULE 1; NOS2 PROTEIN, MOUSE; NOS2A PROTEIN, HUMAN;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; AUTOIMMUNE DISEASE; CONTROLLED STUDY; EDITORIAL; EXPERIMENTAL MODEL; GENETIC TRANSCRIPTION; HEART DISEASE; HISTOPATHOLOGY; IMMUNE SYSTEM; INFLAMMATORY DISEASE; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; ANIMAL; BIOSYNTHESIS; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENE THERAPY; GENETICS; GIANT CELL; HUMAN; IMMUNOLOGY; METABOLISM; NOTE; T LYMPHOCYTE;

ANIMALS; AUTOIMMUNE DISEASES; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENE THERAPY; GIANT CELLS; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; LIPOSOMES; MICE; MYOCARDITIS; NF-KAPPA B; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); T-LYMPHOCYTES;

EID: 0035834244     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/res.89.10.850     Document Type: Editorial

References (13)

1. Advances in the understanding of myocarditis
2. Essential role for the tyrosine kinase p561ck in coxsackievirus B3 mediated heart disease
3. Cellular and molecular mechanisms of murine autoimmune myocarditis
4. Cardiac myosin induces myocarditis in genetically predisposed mice
5. Generation of humanized mice susceptible to peptide-induced inflammatory heart disease
6. Low-molecular weight tumor necrosis factor receptor p55 controls induction of autoimmune heart disease
7. The role of inducible nitric oxide synthase in the host response to Coxsackievirus myocarditis
8. Dissection of TNF receptor 1 effector function: JNK activation is not linked to apoptosis while NF-κB activation prevents cell death
9. Activation of IκB α kinase complex by MEKK1, a kinase of the JNK pathway
10. NF-κB: Pivotal mediator or innocent bystander in atherogenesis?
11. Selective inhibition of NF-κB activation by a peptide that blocks the interaction of NEMO with the IκB kinase complex
12. cis Element decoy against nuclear factor-κB attenuates development of experimental autoimmune myocarditis in rats
13. Application of transcription factor "decoy" strategy as means of gene therapy and study of gene expression in cardiovascular disease