Evaluation of in vitro percutaneous absorption of lorazepam and clonazepam from hydro-alcoholic gel formulations

International Journal of Pharmaceutics

Volumn 228, Issue 1-2, 2001, Pages 79-87

  Puglia, Carmelo ^a   Bonina, Francesco ^a   Trapani, Giuseppe ^b   Franco, Massimo ^b   Ricci, Maurizio ^c  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c UNIVERSITY OF PERUGIA   (Italy)

Author keywords

Clonazepam; In vitro; Lorazepam; Penetration enhancers; Transdermal delivery

Indexed keywords

BENZODIAZEPINE; CARBOPOL 934; CLONAZEPAM; DIETHYLENE GLYCOL MONOETHYL ETHER; LAUROCAPRAM; LIMONENE; LORAZEPAM; PROPYLENE GLYCOL;

ADULT; ARTICLE; CALCULATION; CONTROLLED STUDY; DIFFUSION COEFFICIENT; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG MECHANISM; DRUG PENETRATION; DRUG SCREENING; DRUG TRANSPORT; EPIDERMIS; HUMAN; HUMAN TISSUE; HYDROGEL; IN VITRO STUDY; PARTITION COEFFICIENT; PRIORITY JOURNAL; STEADY STATE; STRATUM CORNEUM;

ADULT; ALCOHOLS; AZEPINES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CLONAZEPAM; CYCLOHEXENES; FEMALE; GABA MODULATORS; GELS; HUMANS; KINETICS; LORAZEPAM; MEMBRANES; SKIN ABSORPTION; TERPENES; WATER;

EID: 0035834192     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00806-7     Document Type: Article

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