Biphenyls as surrogates of the steroidal backbone. Part 2: Discovery of a novel family of non-steroidal 5-α-reductase inhibitors

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 13, 2001, Pages 1713-1716

  Lesuisse, Dominique ^a   Gourvest, Jean François ^a   Albert, Eva ^a   Doucet, Bernard ^a   Hartmann, Catherine ^a   Lefrançois, Jean Michel ^a   Tessier, Sophie ^a   Tric, Bernadette ^a   Teutsch, Georges ^a  

^a SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIPHENYL DERIVATIVE; ENZYME INHIBITOR; NONSTEROID 5ALPHA REDUCTASE INHIBITOR; STEROID 5ALPHA REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; ESTROGEN ACTIVITY; IC 50; REACTION ANALYSIS;

BIPHENYL COMPOUNDS; ENZYME INHIBITORS; STEROIDS; STRUCTURE-ACTIVITY RELATIONSHIP; TESTOSTERONE 5-ALPHA-REDUCTASE;

EID: 0035833064     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00268-2     Document Type: Article

References (18)