Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 13, 2001, Pages 1625-1628

  Massa, Mark A ^a   Spangler, Dale P ^a   Durley, Richard C ^a   Hickory, Brian S ^a   Connolly, Daniel T ^a   Witherbee, Bryan J ^a   Smith, Mark E ^a   Sikorski, James A ^a  

^a Pharmacia Discovery Research   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 PROPANOL; AROMATIC 3 TETRAFLUOROETHOXY; AROMATIC COMPOUND; CHOLESTEROL ESTER TRANSFER PROTEIN; PROTEIN INHIBITOR; TRIFLUORO 3 (TERTIARYAMINO) 2 PROPANOL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; GLYCOPROTEINS; PROPANOLS;

TRIFLUORO;

EID: 0035833027     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00244-X     Document Type: Article

References (15)