Discovery of chiral N,N-disubstituted trifluoro-3-amino-2-propanols as potent inhibitors of cholesteryl ester transfer protein [1]

Journal of Medicinal Chemistry

Volumn 43, Issue 24, 2000, Pages 4575-4578

  Durley, R C ^a   Grapperhaus, M L ^a   Massa, M A ^a   Mischke, D A ^a   Parnas, B L ^a   Fobian, Y M ^a   Rath, N P ^a   Honda, D D ^a   Zeng, M ^a   Connolly, D T ^a   Heuvelman, D M ^a   Witherbee, B J ^a   Glenn, K C ^a   Krul, E S ^a   Smith, M E ^a   Sikorski, J A ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; N,N TRIFLUORO 3 AMINO 2 PROPANOL; UNCLASSIFIED DRUG;

CHEMICAL STRUCTURE; CHIRALITY; LETTER; PROTEIN TRANSPORT; SYNTHESIS;

CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; CRYSTALLOGRAPHY, X-RAY; GLYCOPROTEINS; HUMANS; PROPANOLAMINES; STEREOISOMERISM;

EID: 0034736149     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000337b     Document Type: Letter

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