The role of δ-opioid receptor subtypes in neuropathic pain

European Journal of Pharmacology

Volumn 415, Issue 1, 2001, Pages 31-37

  Mika, Joanna ^a   Przewlocki, Ryszard ^a   Przewlocka, Barbara ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Opioid receptor subtypes; Allodynia; Hyperalgesia; Neuropathic pain

Indexed keywords

5' NALTRINDOLE IZOTIOCYANATE; 7 BENZYLIDENENALTREXONE; DELTORPHIN; ENKEPHALIN; NALTRINDOLE; SIGMA OPIATE RECEPTOR; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIC ACTIVITY; ANALYTIC METHOD; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; LONG TERM EXPOSURE; MALE; NERVE INJURY; NONHUMAN; PAIN; PAIN RECEPTOR; PRIORITY JOURNAL; RAT; REACTION TIME; SCIATIC NERVE; STIMULUS RESPONSE; WITHDRAWAL REFLEX;

ANALGESICS, OPIOID; ANIMALS; BEHAVIOR, ANIMAL; BENZYLIDENE COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, D-PENICILLAMINE (2,5)-; ISOTHIOCYANATES; MALE; NALTREXONE; NARCOTIC ANTAGONISTS; NEURALGIA; OLIGOPEPTIDES; PAIN MEASUREMENT; PROTEIN ISOFORMS; RATS; RATS, WISTAR; RECEPTORS, OPIOID, DELTA; SCIATIC NERVE; TIME FACTORS;

EID: 0035831203     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(01)00814-7     Document Type: Article

References (23)

1. Pre- and post-synaptic distribution of mu, delta and kappa opioid receptors in the superficial layers of the cervical dorsal horn of the rat spinal cord
2. Effects of chronic administration of 7-benzylidene-7-dehydronaltrexone and naltriben on the antinociceptive actions of delta 1- and delta 2-opioid receptor agonists
3. Characterization of the antiallodynic efficacy of morphine in a model of neuropathic pain in rats
4. Studies in vivo with ICI 174864 and [D-Pen2, D-Pen5]enkephalin
5. Methods for producing a reproducible crush in the sciatic and tibial nerve of the rat and rapid and precise testing of return of sensory function. Beneficial effects of melanocortins
6. The effect of novel anti-epileptic drugs in rat experimental models of acute and chronic pain
7. Modulation of the potency and efficacy of mu-mediated antinociception by delta agonist in the mouse
8. Differential mediation of cold water swim stress-induced antinociception by delta-opioid receptor subtypes in diabetic mice
9. Treatment with antisense oligodeoxynucleotide to the opioid δ receptor selectively inhibits δ2-agonist antinociception
10. Antinociceptive effects of isoleucine derivatives of deltorphin I and deltorphin II in rat spinal cord: A search for selectivity of delta receptor subtypes
11. Spinal opioid delta antinociception in the mouse: Mediation by a 5′-NTII-sensitive delta receptor subtype
12. Hypoxia decreases opioid delta receptor expression in mouse brain
13. Topographical requirements for delta opioid ligands: Presence of a carboxyl group in position 4 is not critical for deltorphin high delta receptor affinity and analgesic activity
14. Opposite role of delta 1- and delta 2-opioid receptors activated by endogenous or exogenous opioid agonists on the endogenous cholecystokinin system: Further evidence for delta-opioid receptor heterogeneity
15. Opioid antagonists and antisera to endogenous opioids increase the nociceptive response to formalin: Demonstration of an opioid kappa and delta inhibitory tone
16. Mapping of opioid receptors using antisense oligodeoxynucleotides: Correlating their molecular biology in pharmacology
17. Spinal analgesic action of endomorphins in acute, inflammatory and neuropathic pain in rats
18. Selective antagonists at the opiate delta-receptor
19. Antinociception after intracerebroventricular administration of naltrindole in the mouse
20. Bilateral and differential changes in spinal mu, delta and kappa opioid binding in rats with a painful, unilateral neuropathy
21. Evidence for delta opioid receptor subtypes in rat spinal cord: Studies with intrathecal naltriben, cyclic[D-Pen2, D-Pen5] enkephalin and [D-Ala2, Glu4]deltorphin
22. Interaction of [D-Pen2, D-Pen5]enkephalin and [D-Ala2, Glu4]deltorphin with delta-opioid receptor subtypes in vivo
23. Chronic catheterization of the spinal subarachnoid space