Cooperative effects by the initiation codon and its flanking regions on translation initiation

Gene

Volumn 273, Issue 2, 2001, Pages 259-265

  Stenstrom C Magnus ^a   Holmgren, Erik ^b   Isaksson, Leif A ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

^b Department of Structural Chemistry Pharmacia ^*  (Sweden)

Author keywords

Context; Downstream region; Escherichia coli; Initiation codons; Shine Dalgarno sequence

Indexed keywords

INITIATION FACTOR; MESSENGER RNA; PURINE; RIBOSOME RNA; RNA 16S;

ARTICLE; CODON USAGE; CROSS LINKING; DNA FLANKING REGION; DNA SEQUENCE; ESCHERICHIA COLI; GENE EXPRESSION; GENE SEQUENCE; PRIORITY JOURNAL; START CODON; TRANSLATION INITIATION;

BASE SEQUENCE; BETA-GALACTOSIDASE; CODON, INITIATOR; DNA, BACTERIAL; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, BACTERIAL; LAC OPERON; NUCLEIC ACID CONFORMATION; PLASMIDS; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

ESCHERICHIA COLI;

EID: 0035827918     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(01)00584-4     Document Type: Article

References (36)

1. The database of ribosomal cross-links: An update
2. Amino acid composition of protein termini are biased in different manners
3. Test system for measurement of translational activity in vivo
4. Transcription of single-copy hybrid lacZ genes by T7 RNA polymerase in Escherichia coli: mRNA synthesis and degradation can be uncoupled from translation
5. Selection of aminoacyl-tRNAs at sense codons: The size of the tRNA variable loop determines whether the immediate 3′ nucleotide to the codon has a context effect
6. Control of translation by mRNA secondary structure in Escherichia coli
7. What constitutes the signal for the initiation of protein synthesis on Escherichia coli mRNAs?
8. Point mutations that affect translation initiation in the Escherichia coli gal E gene
9. Translational enhancement by an element downstream of the initiation codon in Escherichia coli
10. Codon choice and potential complementarity between mRNA downstream of the initiation codon and bases 1471-1480 in the 16S ribosomal RNA affects expression of gln S
11. More than 150 nucleotides flanking the initiation codon contribute to the efficiency of the ribosomal binding site from bacteriophage T7 gene 1
12. Posttranscriptional regulatory mechanisms in Escherichia coli
13. Recognition of messenger RNA during translational initiation in Escherichia coli
14. Influence of messenger-RNA determinants on translation initiation in Escherichia coli
15. An unstructured mRNA region and a 5′ hairpin represent important elements of the E. coli translation initiation signal determined by using the bacteriophage T7 gene 1 translation start site
16. Footprinting mRNA-ribosome complexes with chemical probes
17. Initiation of translation in prokaryotes and eukaryotes
18. Codon bias and gene expression
19. Secondary structure as primary determinant of the efficiency of ribosomal binding sites in Escherichia coli
20. Influence of the codon following the AUG initiation codon on the expression of a modified lacZ gene in Escherichia coli
21. Enhancement of translational efficiency by the Escherichia coli atpE gene translational initiation region: Its fusion with two human genes
22. Discrimination by Escherichia coli initiation factor IF3 against initiation on non-canonical codons relies on complementarity rules
23. Specific protection of 16S rRNA by translational initiation factors
24. The second to last amino acid in the nascent peptide as a codon context determinant
25. An engineered class I transfer RNA with a class II tertiary fold
26. Enhancement of translation by the downstream box does not involve base pairing of mRNA with the penultimate stem sequence of 16S rRNA
27. Multiple determinants of functional mRNA stability: Sequence alterations at either end of the lacZ gene affect the rate of mRNA inactivation
28. The role of the AUU initiation codon in the negative feedback regulation of the gene for translation initiation factor IF3 in Escherichia coli
29. Information content of binding sites on nucleotide sequences
30. The path of mRNA through the bacterial ribosome: A site-directed crosslinking study using new photoreactive derivatives of guanosine and uridine
31. The structure of the translational initiation factor IF1 from E. coli contains an oligomer-binding motif
32. The 3′-terminal sequence of Escherichia coli 16S ribosomal RNA: Complementarity to nonsense triplets and ribosome binding sites
33. Codon bias at the 3′-side of the initiation codon is correlated with translation initiation efficiency in Escherichia coli
34. Characterization of translational initiation sites in E. coli
35. Escherichia coli translation initiation factor 3 discriminates the initiation codon in vivo