An endothelin-1-induced model of chronic optic nerve ischemia in rhesus monkeys

Journal of Glaucoma

Volumn 5, Issue 2, 1996, Pages 135-138

  Orgül, Selim ^a  

^a DEVERS EYE INSTITUTE   (United States)

Author keywords

Blood flow; Glaucoma posterior segment; Optic nerve

Indexed keywords

ENDOTHELIN 1; MICROSPHERE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; GLAUCOMA; INTRAOCULAR PRESSURE; MINIPUMP; NONHUMAN; OPTIC NERVE DISEASE; OPTIC NERVE LESION; PRIORITY JOURNAL; RHESUS MONKEY; STATISTICAL ANALYSIS;

ANIMALS; CHRONIC DISEASE; ENDOTHELIN-1; INTRAOCULAR PRESSURE; ISCHEMIA; MACACA MULATTA; MICROSPHERES; OPTIC NERVE; REGIONAL BLOOD FLOW;

EID: 0029874547     PISSN: 10570829     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Van Buskirk EM, Cioffi GA. Glaucomatous optic neuropathy. Am J Ophthalmol 1992;113:447-52.
2. Cioffi GA, Orgül S, Onda E, Bacon DR, Van Buskirk EM. An in vivo model of chronic optic nerve ischemia: the dose-dependent effects of endothelin-1 on the optic nerve microvasculature. Curr Eye Res 1995;14:1147-53.
3. Hoffman WE, Miletich DJ, Albracht RF, Anderson S. Regional cerebral blood flow measurement in rats with radioactive microspheres. Life Sci 1983;33:1075-80.
4. Geijer C, Bill A. Effects of raised intraocular pressure on retinal, prelaminar, and retrolaminar optic nerve blood flow in monkeys. Invest Ophthalmol Vis Sci 1979;18:1030-42.
5. Orgul S, Cioffi GA, Bacon DR, Van Buskirk EM. Measurement of optic nerve blood flow with nonradioactive colored microspheres in rabbits. Microvasc Res 1995;(in press).