Very large long-term effective population size in the virulent human malaria parasite Plasmodium falciparum

Proceedings of the Royal Society B: Biological Sciences

Volumn 268, Issue 1478, 2001, Pages 1855-1860

  Hughes, A L ^a   Verra, F ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Effective population size; Genetic polymorphism; Malaria; Plasmodium falciparum

Indexed keywords

NUCLEAR PROTEIN; NUCLEOTIDE;

MALARIA; PARASITE; POPULATION SIZE;

AMINO ACID SUBSTITUTION; ARTICLE; GENETIC POLYMORPHISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYLOGENY; PLASMODIUM FALCIPARUM; POPULATION; PRIORITY JOURNAL;

PLASMODIUM FALCIPARUM; PROTOZOA;

EID: 0035823291     PISSN: 09628452     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rspb.2001.1759     Document Type: Article

References (36)

1. Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum
2. A clonal Plasmodium falciparum in an isolated outbreak of malaria in the Republic of Cabo Verde
3. Sequence variations in the genes encoding dihydropteroate synthase and dihydrofolate reductase and clinical response to sulfadoxine -pyrimethamine in patients with acute uncomplicated falciparum malaria
4. New genes sweep clean
5. Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase
6. The clay feet of the malaria giant and its African roots: Hypotheses and inferences about origin, spread and control of Plasmodium falciparum
7. Phylogeny of the malarial genus Plasmodium derived from rRNA gene sequences
8. The evolution of primate malaria parasites based on the gene encoding cytochrome b from the linear mitochondrial genome
9. Estimating effective population size from samples of sequences: Inefficiency of pairwise and segregating sites as compared to phylogenetic estimates
10. Apolipoprotein E variation at the sequence haplotype level: Implications for the origin and maintenance of human polymorphism
11. Circumsporozoite proteins of malaria parasites (Plasmodium spp.): Evidence for positive selection on immunogenic regions
12. Positive selection and interallelic recombination at the merozoite surface antigen-1 (MSA-1) locus of Plasmodium falciparum
13. Natural selection on the peptide-binding regions of major histocompatibility complex molecules
14. Natural selection on Plasmodium surface proteins
15. Pattern of nucleotide substitution at MHC class I loci reveals overdominant selection
16. Ancient polymorphism and the hypothesis of a recent bottleneck in the malaria parasite Plasmodium falciparum
17. A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms
18. Estimating effective population size and mutation rate from sequence data using Metropolis-Hasting sampling
19. Maximum likelihood estimation of population growth rates based on the coalescent
20. Low nucleotide diversity in man
21. Anthropological implications of sickle cell gene distribution in West Africa
22. Genetic restriction of Plasmodium falciparum in an area of stable transmission: An example of island evolution?
23. Estimation of the amount of DNA polymorphism when the neutral mutation rate varies among sites
24. The epidemiology of human malaria as an explanation of its distribution, including some implications for its control
25. Simple methods for estimating the numbers of synonymous and non-synonymous nucleotide substitutions
26. Adjusting the focus on human variation
27. Malaria's Eve: Evidence of a recent population bottleneck throughout the world population of Plasmodium falciparum
28. Evolutionary relationship of DNA sequences in finite populations
29. The amount of DNA polymorphism maintained in a finite population when the neutral mutation rate varies among sites
30. Allelic genealogy under over-dominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci
31. Estimation of the number of nucleotide substitutions in the control region of mitochondrial DNA in humans and chimpanzees
32. Evidence for ancient balanced polymorphism at the apical membrane antigen-1 (AMA-1) locus of Plasmodium falciparum
33. On the number of segregating sites in genetic models without recombination
34. World malaria situation in 1994