Tumor necrosis factor-α drives HIV-1 replication in U937 cell clones and upregulates CXCR4

Cytokine

Volumn 13, Issue 1, 2001, Pages 55-59

  Biswas, Priscilla ^a   Mantelli, Barbara ^a   Delfanti, Fanny ^a   Cota, Manuela ^a   Vallanti, Giuliana ^a   De Filippi, Camilla ^a   Mengozzi, Manuela ^a   Vicenzi, E ^a   Lazzarin, A ^a   Poli, Guido ^a  

^a SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

CXCR4; HIV 1; TNF ; U937

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; TUMOR NECROSIS FACTOR ALPHA; VIRUS DNA;

ARTICLE; CELL CLONE; CONTROLLED STUDY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; PRIORITY JOURNAL; PROVIRUS; RECEPTOR DENSITY; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0035819237     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1006/cyto.2000.0798     Document Type: Article

References (14)

1. A family of serine proteases expressed exclusively in myelo-monocytic cells specifically processes the nuclear factor-kB subunit p65 in vitro and may impair human immunodeficiency virus replication in these cells
2. Susceptibility to infection by the human immunodeficiency virus (HIV) correlates with T4 expression in a parental monocytoid cell line and its subclones
3. Differential susceptibilities of U-937 cell clones to infection by human immunodeficiency virus type 1
4. Promonocytic U937 subclones expressing CD4 and CXCR4 are resistant to infection with and cell-to-cell fusion by T-cell-tropic human immunodeficiency virus type 1
5. 1,25-dihydroxyvitamin D3 upregulates functional CXCR4 human immunodeficiency virus type 1 coreceptors in U937 minus clones: NF-kB-independent enhancement of viral replication
6. Increased human immunodeficiency virus (HIV) expression in chronically infected U937 cells upon in vitro differentiation by hydroxyvitamin D3: Roles of interferon and tumor necrosis factor in regulation of HIV production
7. Tumor necrosis factor-alpha/cachectin enhances human immunodeficiency virus type 1 replication in primary macrophages
8. Cytokine modulation of HIV infection
9. HIV replication in IL-2-stimulated peripheral blood mononuclear cells is driven in an autocrine/paracrine manner by endogenous cytokines
10. Changes in CXC-chemokine receptor-4 expression during HIV-1 replication are independent of CD4 modulations
11. Interferon downregulates CXCR4 (fusin) gene expression in peripheral blood mononuclear cells
12. Cloning and analysis of the promoter region of CXCR4, a coreceptor for HIV-1 entry
13. Endothelial cells differentially express functional CXC-chemokine receptor-4 (CXCR4/fusin) under the control of autocrine activity and exogenous cytokines
14. Envelope-dependent restriction of human immunodeficiency virus type 1 spreading in CD4+ T lymphocytes: R5 but not X4 viruses replicate in the absence of T-cell receptor restimulation