αvβ3 antagonists based on a central thiophene scaffold

Bioorganic and Medicinal Chemistry Letters

Volumn 11, Issue 15, 2001, Pages 2011-2015

  Peyman, Anusch ^a   Scheunemann, Karl Heinz ^a   Will, David W ^a   Knolle, Jochen ^a   Wehner, Volkmar ^a   Breipohl, Gerhard ^a   Stilz, Hans Ulrich ^a   Carniato, Denis ^b   Ruxer, Jean Marie ^b   Gourvest, Jean Francois ^b   Auberval, Marielle ^b   Doucet, Bernard ^b   Baron, Roland ^b   Gaillard, Martine ^b   Gadek, Thomas R ^c   Bodary, Sarah ^c  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b SANOFI   (France)

^c GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BETA AMINO ACID; CARBAMIC ACID DERIVATIVE; GUANIDINE DERIVATIVE; SULFONAMIDE; THIOPHENE DERIVATIVE; UNCLASSIFIED DRUG; VITRONECTIN RECEPTOR; VITRONECTIN RECEPTOR ANTAGONIST;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DRUG BINDING; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPOPHILICITY; OSTEOLYSIS; OSTEOPOROSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ANIMALS; BINDING SITES; CARBAMATES; CELL ADHESION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINE; OSTEOPOROSIS; PARATHYROIDECTOMY; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RATS; RECEPTORS, VITRONECTIN; SENSITIVITY AND SPECIFICITY; SULFONAMIDES; THIOPHENES; THYROIDECTOMY;

EID: 0035817220     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(01)00357-2     Document Type: Article

References (8)