The Cell Cycle Inhibitor p16INK4A Sensitizes Lymphoblastic Leukemia Cells to Apoptosis by Physiologic Glucocorticoid Levels

Journal of Biological Chemistry

Volumn 276, Issue 14, 2001, Pages 10984-10989

  Ausserlechner, Michael J ^a   Obexer, Petra ^a   Wiegers, G Jan ^a   Hartmann, Bernd L ^a   Geley, Stephan ^a   Kofler, Reinhard ^a,b,c  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b TYROLEAN CANCER RESEARCH INSTITUTE   (Austria)

^c Institute of General and Experimental Pathology   (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYME INHIBITION; GENES; PROTEINS; TUMORS;

APOPTOSIS; SENSITIVITY THRESHOLD;

BIOCHEMISTRY;

CYCLIN D3; CYCLIN DEPENDENT KINASE INHIBITOR; DEXAMETHASONE; DOXYCYCLINE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; HYGROMYCIN B; MIFEPRISTONE; PROTEIN P16; PROTEIN P16INK4A; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; RECOMBINANT PROTEIN;

APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; GENE DELETION; GENE INACTIVATION; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RETINOBLASTOMA; T CELL LEUKEMIA; CELL CULTURE; GENETICS; INTERPHASE; METABOLISM; MOLECULAR CLONING; PATHOLOGY; PHYSIOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; SIGNAL TRANSDUCTION;

APOPTOSIS; CELL CYCLE; CLONING, MOLECULAR; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE DELETION; GLUCOCORTICOIDS; HUMANS; INTERPHASE; LEUKEMIA, T-CELL, ACUTE; RECEPTORS, GLUCOCORTICOID; RECOMBINANT PROTEINS; TUMOR CELLS, CULTURED; GENE EXPRESSION REGULATION, NEOPLASTIC; SIGNAL TRANSDUCTION;

EID: 0035815695     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M008188200     Document Type: Article

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