Functional modulation of gamma-aminobutyric acidA receptors by etifoxine and allopregnanolone in rodents

Neuroscience Letters

Volumn 301, Issue 3, 2001, Pages 191-194

  Verleye, M ^a   Schlichter, R ^b   Neliat, G ^c   Pansart, Y ^a   Gillardin, J M ^a  

^a Service de Pharmacologie   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c CEREP   (France)

Author keywords

(+)Bicuculline; 35S t Butylbicyclophosphorothionate binding; Additive effect; Allopregnanolone; Allosteric modulator; Anticonvulsant; Anxiolytic; Etifoxine

Indexed keywords

3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ANTICONVULSIVE AGENT; BICUCULLINE; CHLORIDE CHANNEL; ETIFOXINE; NEUROSTEROID; SULFUR 35; TERT BUTYLBICYCLOPHOSPHOROTHIOATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CLONIC SEIZURE; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFECT; DRUG POTENTIATION; IC 50; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALLOSTERIC SITE; ANIMALS; ANTICONVULSANTS; BICUCULLINE; BICYCLO COMPOUNDS, HETEROCYCLIC; CHLORIDE CHANNELS; CONVULSANTS; DRUG INTERACTIONS; GABA ANTAGONISTS; MALE; OXAZINES; PREGNANOLONE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SULFUR RADIOISOTOPES;

EID: 0035815577     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01647-0     Document Type: Article

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