Effect of different concentrations of iontophoretic nociceptin on distinct classes of nociceptive neurons in rat spinal cord

Brain Research

Volumn 897, Issue 1-2, 2001, Pages 184-187

  Sotgiu, Maria Luisa ^a   Bellomi, Paola ^a,b   Biella, Gabriele ^a,c  

^a CNR   (Italy)

^b Schering Plough Research Institute   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Nociceptin; Nociceptive specific neuron; Noxious evoked activity; Rat; Wide dynamic range neuron

Indexed keywords

NALOXONE; NOCICEPTIN;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; DRUG EFFECT; DRUG MEGADOSE; IONTOPHORESIS; NERVE CELL; NOCICEPTIVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; IONTOPHORESIS; NEURONS, AFFERENT; NOCICEPTORS; OPIOID PEPTIDES; PAIN; PHYSICAL STIMULATION; RATS; SPINAL CORD;

EID: 0035815549     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(01)02155-2     Document Type: Article

References (20)

1. Immunohistochemical localization of ORL-1 in the central nervous system of the rat
2. Unaltered peripheral excitatory actions of nociceptin contrast with enhanced spinal inhibitory effects after carrageenan inflammation: An electrophysiological study in the rat
3. Orphanin FQ/nociceptin: A role in pain and analgesia, but so much more
4. Depression of glutamatergic transmission by nociceptin in the neonatal rat hemisected spinal cord preparation in vitro
5. Inhibition of tachykinin release from peripheral endings of sensory nerves by nociceptin, a novel opioid peptide
6. Rough annealing by two step clustering, with application to neuronal signals
7. The orphan opioid receptor and its endogenous ligand-nociceptin/orphanin FQ
8. Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation
9. Nociceptin-like immunoreactivity in the dorsal horn and inhibition of substantia gelatinosa neurons
10. Modulation of excitatory synaptic transmission by nociceptin in superficial dorsal horn neurons of the neonatal rat spinal cord
11. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
12. Localization of Orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat
13. Orphanin FQ: A neuropeptide that activates an opioid-like G protein-coupled receptor
14. Post-stimulus after discharges of spinal WDR and NS units in rats with chronic nerve constriction
15. Inhibitory action of nociceptin on spinal dorsal horn of the rat, in vivo
16. Orphanin FQ (nociceptin) modulates responses of trigeminal neurons evoked by excitatory amino acids and somatosensory stimuli, and blocks the substance P-induced facilitation of N-methyl-D-aspartate-evoked responses
17. Nociceptin/orphanin FQ: Role in nociceptive information processing
18. Ethical guidelines for investigation of experimental pain in conscious animals